| Reaction Details |
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 | Report a problem with these data |
| Target | Hexokinase HKDC1 [W721R] |
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| Ligand | BDBM48647 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of activators of hexokinase domain containing I (HKDC1) |
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| EC50 | >80000±n/a nM |
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| Citation |  PubChem, PC Dose Response confirmation of activators of hexokinase domain containing I (HKDC1) PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Hexokinase HKDC1 [W721R] |
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| Name: | Hexokinase HKDC1 [W721R] |
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| Synonyms: | HKDC1 | HKDC1_HUMAN | putative hexokinase HKDC1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 102520.24 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_156151420 |
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| Residue: | 917 |
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| Sequence: | MFAVHLMAFYFSKLKEDQIKKVDRFLYHMRLSDDTLLDIMRRFRAEMEKGLAKDTNPTAA
VKMLPTFVRAIPDGSENGEFLSLDLGGSKFRVLKVQVAEEGKRHVQMESQFYPTPNEIIR
GNGTELFEYVADCLADFMKTKDLKHKKLPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGV
QDTDVVSRLTKAMRRHKDMDVDILALVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYME
DMSNIDLVEGDEGRMCINTEWGAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGL
YLGELVRLILLKMAKAGLLFGGEKSSALHTKGKIETRHVAAMEKYKEGLANTREILVDLG
LEPSEADCIAVQHVCTIVSFRSANLCAAALAAILTRLRENKKVERLRTTVGMDGTLYKIH
PQYPKRLHKVVRKLVPSCDVRFLLSESGSTKGAAMVTAVASRVQAQRKQIDRVLALFQLT
REQLVDVQAKMRAELEYGLKKKSHGLATVRMLPTYVCGLPDGTEKGKFLALDLGGTNFRV
LLVKIRSGRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLKGASLPLGFT
FSFPCRQMSIDKGTLIGWTKGFKATDCEGEDVVDMLREAIKRRNEFDLDIVAVVNDTVGT
MMTCGYEDPNCEIGLIAGTGSNMCYMEDMRNIEMVEGGEGKMCINTEWGGFGDNGCIDDI
RTRYDTEVDEGSLNPGKQRYEKMTSGMYLGEIVRQILIDLTKQGLLFRGQISERLRTRGI
FETKFLSQIESDRLALLQVRRILQQLGLDSTCEDSIVVKEVCGAVSRRAAQLCGAGLAAI
VEKRREDQGLEHLRITVGVDGTLYKLHPHFSRILQETVKELAPRCDVTFMLSEDGSGKGA
ALITAVAKRLQQAQKEN
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| BDBM48647 |
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| n/a |
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| Name | BDBM48647 |
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| Synonyms: | 2-[[2-[[1-(4-methoxyphenyl)-5-tetrazolyl]thio]-1-oxoethyl]amino]-4,5-dimethyl-3-thiophenecarboxylic acid ethyl ester | 2-[[2-[[1-(4-methoxyphenyl)tetrazol-5-yl]thio]acetyl]amino]-4,5-dimethyl-thiophene-3-carboxylic acid ethyl ester | MLS000538903 | SMR000144740 | cid_2238453 | ethyl 2-[({[1-(4-methoxyphenyl)-1H-tetrazol-5-yl]thio}acetyl)amino]-4,5-dimethyl-3-thiophenecarboxylate | ethyl 2-[2-[[1-(4-methoxyphenyl)-1,2,3,4-tetrazol-5-yl]sulfanyl]ethanoylamino]-4,5-dimethyl-thiophene-3-carboxylate | ethyl 2-[[2-[1-(4-methoxyphenyl)tetrazol-5-yl]sulfanylacetyl]amino]-4,5-dimethylthiophene-3-carboxylate |
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| Type | Small organic molecule |
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| Emp. Form. | C19H21N5O4S2 |
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| Mol. Mass. | 447.531 |
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| SMILES | CCOC(=O)c1c(C)c(C)sc1NC(=O)CSc1nnnn1-c1ccc(OC)cc1 |
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| Structure | 
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