| Reaction Details |
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 | Report a problem with these data |
| Target | Hexokinase HKDC1 [W721R] |
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| Ligand | BDBM80778 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of activators of hexokinase domain containing I (HKDC1) |
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| EC50 | 13600±n/a nM |
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| Citation |  PubChem, PC Dose Response confirmation of activators of hexokinase domain containing I (HKDC1) PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Hexokinase HKDC1 [W721R] |
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| Name: | Hexokinase HKDC1 [W721R] |
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| Synonyms: | HKDC1 | HKDC1_HUMAN | putative hexokinase HKDC1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 102520.24 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_156151420 |
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| Residue: | 917 |
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| Sequence: | MFAVHLMAFYFSKLKEDQIKKVDRFLYHMRLSDDTLLDIMRRFRAEMEKGLAKDTNPTAA
VKMLPTFVRAIPDGSENGEFLSLDLGGSKFRVLKVQVAEEGKRHVQMESQFYPTPNEIIR
GNGTELFEYVADCLADFMKTKDLKHKKLPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGV
QDTDVVSRLTKAMRRHKDMDVDILALVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYME
DMSNIDLVEGDEGRMCINTEWGAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGL
YLGELVRLILLKMAKAGLLFGGEKSSALHTKGKIETRHVAAMEKYKEGLANTREILVDLG
LEPSEADCIAVQHVCTIVSFRSANLCAAALAAILTRLRENKKVERLRTTVGMDGTLYKIH
PQYPKRLHKVVRKLVPSCDVRFLLSESGSTKGAAMVTAVASRVQAQRKQIDRVLALFQLT
REQLVDVQAKMRAELEYGLKKKSHGLATVRMLPTYVCGLPDGTEKGKFLALDLGGTNFRV
LLVKIRSGRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLKGASLPLGFT
FSFPCRQMSIDKGTLIGWTKGFKATDCEGEDVVDMLREAIKRRNEFDLDIVAVVNDTVGT
MMTCGYEDPNCEIGLIAGTGSNMCYMEDMRNIEMVEGGEGKMCINTEWGGFGDNGCIDDI
RTRYDTEVDEGSLNPGKQRYEKMTSGMYLGEIVRQILIDLTKQGLLFRGQISERLRTRGI
FETKFLSQIESDRLALLQVRRILQQLGLDSTCEDSIVVKEVCGAVSRRAAQLCGAGLAAI
VEKRREDQGLEHLRITVGVDGTLYKLHPHFSRILQETVKELAPRCDVTFMLSEDGSGKGA
ALITAVAKRLQQAQKEN
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| BDBM80778 |
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| n/a |
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| Name | BDBM80778 |
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| Synonyms: | 3-(2-ketochromen-3-yl)-N-(4-pyrrolidinophenyl)benzamide | 3-(2-oxidanylidenechromen-3-yl)-N-(4-pyrrolidin-1-ylphenyl)benzamide | 3-(2-oxo-1-benzopyran-3-yl)-N-[4-(1-pyrrolidinyl)phenyl]benzamide | 3-(2-oxo-2H-chromen-3-yl)-N-[4-(1-pyrrolidinyl)phenyl]benzamide | 3-(2-oxochromen-3-yl)-N-(4-pyrrolidin-1-ylphenyl)benzamide | MLS000579375 | SMR000198658 | cid_1864167 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H22N2O3 |
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| Mol. Mass. | 410.4645 |
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| SMILES | O=C(Nc1ccc(cc1)N1CCCC1)c1cccc(c1)-c1cc2ccccc2oc1=O |
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| Structure | 
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