| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Hexokinase HKDC1 [W721R] |
|---|
| Ligand | BDBM80785 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Dose Response confirmation of activators of hexokinase domain containing I (HKDC1) |
|---|
| EC50 | 19400±n/a nM |
|---|
| Citation |  PubChem, PC Dose Response confirmation of activators of hexokinase domain containing I (HKDC1) PubChem Bioassay(2011)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Hexokinase HKDC1 [W721R] |
|---|
| Name: | Hexokinase HKDC1 [W721R] |
|---|
| Synonyms: | HKDC1 | HKDC1_HUMAN | putative hexokinase HKDC1 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 102520.24 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | gi_156151420 |
|---|
| Residue: | 917 |
|---|
| Sequence: | MFAVHLMAFYFSKLKEDQIKKVDRFLYHMRLSDDTLLDIMRRFRAEMEKGLAKDTNPTAA
VKMLPTFVRAIPDGSENGEFLSLDLGGSKFRVLKVQVAEEGKRHVQMESQFYPTPNEIIR
GNGTELFEYVADCLADFMKTKDLKHKKLPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGV
QDTDVVSRLTKAMRRHKDMDVDILALVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYME
DMSNIDLVEGDEGRMCINTEWGAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGL
YLGELVRLILLKMAKAGLLFGGEKSSALHTKGKIETRHVAAMEKYKEGLANTREILVDLG
LEPSEADCIAVQHVCTIVSFRSANLCAAALAAILTRLRENKKVERLRTTVGMDGTLYKIH
PQYPKRLHKVVRKLVPSCDVRFLLSESGSTKGAAMVTAVASRVQAQRKQIDRVLALFQLT
REQLVDVQAKMRAELEYGLKKKSHGLATVRMLPTYVCGLPDGTEKGKFLALDLGGTNFRV
LLVKIRSGRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLKGASLPLGFT
FSFPCRQMSIDKGTLIGWTKGFKATDCEGEDVVDMLREAIKRRNEFDLDIVAVVNDTVGT
MMTCGYEDPNCEIGLIAGTGSNMCYMEDMRNIEMVEGGEGKMCINTEWGGFGDNGCIDDI
RTRYDTEVDEGSLNPGKQRYEKMTSGMYLGEIVRQILIDLTKQGLLFRGQISERLRTRGI
FETKFLSQIESDRLALLQVRRILQQLGLDSTCEDSIVVKEVCGAVSRRAAQLCGAGLAAI
VEKRREDQGLEHLRITVGVDGTLYKLHPHFSRILQETVKELAPRCDVTFMLSEDGSGKGA
ALITAVAKRLQQAQKEN
|
|
|
|---|
| BDBM80785 |
|---|
| n/a |
|---|
| Name | BDBM80785 |
|---|
| Synonyms: | (5E)-2,4-dimethyl-5-[2-(p-phenetidino)-4H-1,3,4-thiadiazin-5-ylidene]pyrrole-3-carboxylic acid ethyl ester | (5E)-5-[2-(4-ethoxyanilino)-4H-1,3,4-thiadiazin-5-ylidene]-2,4-dimethyl-3-pyrrolecarboxylic acid ethyl ester | MLS000375273 | SMR000254526 | cid_6095443 | ethyl (5E)-5-[2-(4-ethoxyanilino)-4H-1,3,4-thiadiazin-5-ylidene]-2,4-dimethylpyrrole-3-carboxylate | ethyl (5E)-5-[2-[(4-ethoxyphenyl)amino]-4H-1,3,4-thiadiazin-5-ylidene]-2,4-dimethyl-pyrrole-3-carboxylate |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H24N4O3S |
|---|
| Mol. Mass. | 400.495 |
|---|
| SMILES | CCOC(=O)c1c(C)[nH]c(c1C)C1=NN=C(Nc2ccc(OCC)cc2)SC1 |t:13,15| |
|---|
| Structure | 
|
|---|
Search and Browse
