| Reaction Details |
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 | Report a problem with these data |
| Target | Monoglyceride lipase |
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| Ligand | BDBM81364 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Enzyme Assay |
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| Temperature | 310.15±0 K |
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| IC50 | 4e+3± 5e+2 nM |
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| Citation |  King, AR; Dotsey, EY; Lodola, A; Jung, KM; Ghomian, A; Qiu, Y; Fu, J; Mor, M; Piomelli, D Discovery of potent and reversible monoacylglycerol lipase inhibitors. Chem Biol16:1045-52 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Monoglyceride lipase |
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| Name: | Monoglyceride lipase |
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| Synonyms: | MAGL | MGLL_RAT | Mgl2 | Mgll | Monoacylglycerol lipase | Monoglyceride lipase | Monoglyceride lipase (MGL) |
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| Type: | Enzyme |
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| Mol. Mass.: | 33505.38 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | Q8R431 |
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| Residue: | 303 |
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| Sequence: | MPEASSPRRTPQNVPYQDLPHLVNADGQYLFCRYWKPSGTPKALIFVSHGAGEHCGRYDE
LAQMLKRLDMLVFAHDHVGHGQSEGERMVVSDFQVFVRDLLQHVNTVQKDYPEVPVFLLG
HSMGGAISILAAAERPTHFSGMILISPLILANPESASTLKVLAAKLLNFVLPNISLGRID
SSVLSRNKSEVDLYNSDPLICHAGVKVCFGIQLLNAVSRVERAMPRLTLPFLLLQGSADR
LCDSKGAYLLMESSPSQDKTLKMYEGAYHVLHKELPEVTNSVLHEINTWVSHRIAVAGAR
CLP
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| BDBM81364 |
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| n/a |
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| Name | BDBM81364 |
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| Synonyms: | Pristimerol |
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| Type | Small organic molecule |
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| Emp. Form. | C30H42O4 |
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| Mol. Mass. | 466.6521 |
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| SMILES | COC(=O)[C@]1(C)CC[C@]2(C)CC[C@]3(C)C4=CCc5c(C)c(O)c(O)cc5[C@]4(C)CC[C@@]3(C)C2C1 |r,t:14| |
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| Structure | 
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