| Reaction Details |
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 | Report a problem with these data |
| Target | Potassium voltage-gated channel subfamily H member 8 |
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| Ligand | BDBM50010685 |
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| Substrate/Competitor | n/a |
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| Ki | >10000±n/a nM |
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| Comments | PDSP_664 |
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| Citation |  Mottola, DM; Brewster, WK; Cook, LL; Nichols, DE; Mailman, RB Dihydrexidine, a novel full efficacy D1 dopamine receptor agonist. J Pharmacol Exp Ther262:383-93 (1992) [PubMed] |
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| More Info.: | Get all data from this article |
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| Potassium voltage-gated channel subfamily H member 8 |
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| Name: | Potassium voltage-gated channel subfamily H member 8 |
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| Synonyms: | Elk1 | Elk3 | KCNH8_RAT | Kcnh8 | Potassium Channel | Potassium voltage-gated channel subfamily H member 8 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 123234.95 |
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| Organism: | RAT |
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| Description: | Q9QWS8 |
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| Residue: | 1102 |
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| Sequence: | MPVMKGLLAPQNTFLDTIATRFDGTHSNFILANAQVAKGFPIVYCSDGFCELAGFARTEV
MQKSCSCKFLFGVETNEQLMLQIEKSLEEKVEFKGEIMFYKKNGAPFWCLLDIVPIKNEK
GDVVLFLASFKDITDTKVKITSEDKKEDRAKGRSRAGSHFDSARRRSRAVLYHISGHLQR
REKNKLKINNNVFVDKPAFPEYKVSDAKKSKFILLHFSTFKAGWDWLILLATFYVAVTVP
YNVCFIGNEDLSTTRSTTVSDIAVEILFIIDIILNFRTTYVSKSGQVIFEARSICIHYVT
TWFIIDLIAALPFDLLYAFNVTVVSLVHLLKTVRLLRLLRLLQKLDRYSQHSTIVLTLLM
SMFALLAHWMACIWYVIGKMEREDNSLLKWEVGWLHELGKRLESPYYGNNTLGGPSIRSA
YIAALYFTLSSLTSVGFGNVSANTDAEKIFSICTMLIGALMHALVFGNVTAIIQRMYSRW
SLYHTRTKDLKDFIRVHHLPQQLKQRMLEYFQTTWSVNNGIDSNELLKDFPDELRSDITM
HLNKEILQLSLFECASRGCLRSLSLHIKTSFCAPGEYLLRQGDALQAIYFVCSGSMEVLK
DSMVLAILGKGDLIGANLSIKDQVIKTNADVKALTYCDLQCIILKGLFEVLGLYPEYAHK
FVEDIQHDLTYNLREGHESDVISRLSNKSTVPQAEPKGNGSIKKRLPSIVEDEEEEEVEE
EETTSLSPIYTRGSSVSHSKKTGSSKSYLGLSLKQLTSGTVPFHSPIRVSSANSPKTKQE
ADPPNHGTRKEKNLKVQLCSLGTAGTPELSPRIVDGIEDGNSSEETQTFDFGSEQIRPEP
RISPSLGESEIGAAFLFIKAEETKQQINKLNSEVTTLTQEVSQLGKDMRSIMQLLENILS
PQQPSQFCSLHPTSICPSRESFQTRVSWSAHQPCLHLQANGAHLYHGNVTSDIWSVDPSL
VGSNPQRTEAHEQSPVDSELHHSPNLAYSPSHCQVIQEGHLQFLRCISPHSDTTLTPLQS
ISATLSSSVCSSSETSLHLVLPSRSEEGSITHGPVSSFSLENLPGSWDREGMMSASTEPL
ENFPVEVVTSTADVKDSKAINV
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| BDBM50010685 |
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| n/a |
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| Name | BDBM50010685 |
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| Synonyms: | (+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahydrobenzo[a]phenanthridine | (6aR,12bR)-5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol | 5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol | CHEMBL43345 | Dihydrexidine, DHX |
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| Type | Small organic molecule |
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| Emp. Form. | C17H17NO2 |
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| Mol. Mass. | 267.3224 |
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| SMILES | Oc1cc2CC[C@H]3NCc4ccccc4[C@H]3c2cc1O |
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| Structure | 
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