| Reaction Details |
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 | Report a problem with these data |
| Target | Hyaluronidase-1 |
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| Ligand | BDBM81868 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Morgan-Elson Assay |
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| pH | 3.5±0 |
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| Temperature | 310.15±0 K |
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| IC50 | 5.668e+4±n/a nM |
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| Citation |  Olgen, S; Kaessler, A; Nebioglu, D; Jose, J New potent indole derivatives as hyaluronidase inhibitors. Chem Biol Drug Des70:547-51 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Hyaluronidase-1 |
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| Name: | Hyaluronidase-1 |
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| Synonyms: | HYAL1 | HYAL1_HUMAN | Hyaluronidase | Hyaluronidase-1 | Hyaluronoglucosaminidase-1 | LUCA1 |
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| Type: | Protein |
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| Mol. Mass.: | 48369.09 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q1279 |
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| Residue: | 435 |
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| Sequence: | MAAHLLPICALFLTLLDMAQGFRGPLLPNRPFTTVWNANTQWCLERHGVDVDVSVFDVVA
NPGQTFRGPDMTIFYSSQLGTYPYYTPTGEPVFGGLPQNASLIAHLARTFQDILAAIPAP
DFSGLAVIDWEAWRPRWAFNWDTKDIYRQRSRALVQAQHPDWPAPQVEAVAQDQFQGAAR
AWMAGTLQLGRALRPRGLWGFYGFPDCYNYDFLSPNYTGQCPSGIRAQNDQLGWLWGQSR
ALYPSIYMPAVLEGTGKSQMYVQHRVAEAFRVAVAAGDPNLPVLPYVQIFYDTTNHFLPL
DELEHSLGESAAQGAAGVVLWVSWENTRTKESCQAIKEYMDTTLGPFILNVTSGALLCSQ
ALCSGHGRCVRRTSHPKALLLLNPASFSIQLTPGGGPLSLRGALSLEDQAQMAVEFKCRC
YPGWQAPWCERKSMW
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| BDBM81868 |
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| n/a |
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| Name | BDBM81868 |
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| Synonyms: | N-Substituted indole-2- and 3-carboxamide derivative, 18 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H18F2N2O |
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| Mol. Mass. | 376.3986 |
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| SMILES | Fc1ccc(CNC(=O)c2cn(Cc3ccc(F)cc3)c3ccccc23)cc1 |
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| Structure | 
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