| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Histamine H1 receptor |
|---|
| Ligand | BDBM50022784 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | 6400±n/a nM |
|---|
| Comments | PDSP_1894 |
|---|
| Citation |  Wong, DT; Threlkeld, PG; Best, KL; Bymaster, FP A new inhibitor of norepinephrine uptake devoid of affinity for receptors in rat brain. J Pharmacol Exp Ther222:61-5 (1982) [PubMed] |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| Histamine H1 receptor |
|---|
| Name: | Histamine H1 receptor |
|---|
| Synonyms: | HISTAMINE H1 | HRH1_RAT | Hrh1 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 55716.35 |
|---|
| Organism: | RAT |
|---|
| Description: | HISTAMINE H1 HRH1 RAT::P31390 |
|---|
| Residue: | 486 |
|---|
| Sequence: | MSFANTSSTFEDKMCEGNRTAMASPQLLPLVVVLSSISLVTVGLNLLVLYAVHSERKLHT
VGNLYIVSLSVADLIVGAVVMPMNILYLIMTKWSLGRPLCLFWLSMDYVASTASIFSVFI
LCIDRYRSVQQPLRYLRYRTKTRASATILGAWFFSFLWVIPILGWHHFMPPAPELREDKC
ETDFYNVTWFKIMTAIINFYLPTLLMLWFYVKIYKAVRRHCQHRQLTNGSLPSFSELKLR
SDDTKEGAKKPGRESPWGVLKRPSRDPSVGLDQKSTSEDPKMTSPTVFSQEGERETRPCF
RLDIMQKQSVAEGDVRGSKANDQALSQPKMDEQSLNTCRRISETSEDQTLVDQQSFSRTT
DSDTSIEPGPGRVKSRSGSNSGLDYIKITWKRLRSHSRQYVSGLHLNRERKAAKQLGFIM
AAFILCWIPYFIFFMVIAFCKSCCSEPMHMFTIWLGYINSTLNPLIYPLCNENFKKTFKK
ILHIRS
|
|
|
|---|
| BDBM50022784 |
|---|
| n/a |
|---|
| Name | BDBM50022784 |
|---|
| Synonyms: | (R)-N-methyl-3-phenyl-3-(o-tolyloxy)propan-1-amine | ATOMOXETINE | CHEMBL641 | Methyl-((R)-3-phenyl-3-o-tolyloxy-propyl)-amine | Methyl-(3-phenyl-3-o-tolyloxy-propyl)-amine | Methyl-(3-phenyl-3-o-tolyloxy-propyl)-amine(tomoxetine) | Strattera | Tomoxetine |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H21NO |
|---|
| Mol. Mass. | 255.3547 |
|---|
| SMILES | CNCCC(Oc1ccccc1C)c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
