| Reaction Details |
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 | Report a problem with these data |
| Target | Ephrin type-A receptor 4 [1-949,A922V] |
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| Ligand | BDBM82187 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Enzyme-linked Immunosorbent Assay |
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| pH | 7.5±0 |
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| IC50 | 2.6e+3± 4e+2 nM |
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| Citation |  Noberini, R; De, SK; Zhang, Z; Wu, B; Raveendra-Panickar, D; Chen, V; Vazquez, J; Qin, H; Song, J; Cosford, ND; Pellecchia, M; Pasquale, EB A disalicylic acid-furanyl derivative inhibits ephrin binding to a subset of Eph receptors. Chem Biol Drug Des78:667-78 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Ephrin type-A receptor 4 [1-949,A922V] |
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| Name: | Ephrin type-A receptor 4 [1-949,A922V] |
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| Synonyms: | EPHA4 | EPHA4_HUMAN | HEK8 | SEK | TYRO1 |
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| Type: | Protein |
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| Mol. Mass.: | 105739.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q58F15 |
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| Residue: | 949 |
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| Sequence: | MAGIFYFALFSCLFGICDAVTGSRVYPANEVTLLDSRSVQGELGWIASPLEGGWEEVSIM
DEKNTPIRTYQVCNVMEPSQNNWLRTDWITREGAQRVYIEIKFTLRDCNSLPGVMGTCKE
TFNLYYYESDNDKERFIRENQFVKIDTIAADESFTQVDIGDRIMKLNTEIRDVGPLSKKG
FYLAFQDVGACIALVSVRVFYKKCPLTVRNLAQFPDTITGADTSSLVEVRGSCVNNSEEK
DVPKMYCGADGEWLVPIGNCLCNAGHEERSGECQACKIGYYKALSTDATCAKCPPHSYSV
WEGATSCTCDRGFFRADNDAASMPCTRPPSAPLNLISNVNETSVNLEWSSPQNTGGRQDI
SYNVVCKKCGAGDPSKCRPCGSGVHYTPQQNGLKTTKVSITDLLAHTNYTFEIWAVNGVS
KYNPNPDQSVSVTVTTNQAAPSSIALVQAKEVTRYSVALAWLEPDRPNGVILEYEVKYYE
KDQNERSYRIVRTAARNTDIKGLNPLTSYVFHVRARTAAGYGDFSEPLEVTTNTVPSRII
GDGANSTVLLVSVSGSVVLVVILIAAFVISRRRSKYSKAKQEADEEKHLNQGVRTYVDPF
TYEDPNQAVREFAKEIDASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYT
DKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTV
IQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYT
TRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEG
YRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLDKLIRNPNSLKRTGTESSRPNT
ALLDPSSPEFSAVVSVGDWLQVIKMDRYKDNFTAAGYTTLEAVVHVNQE
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| BDBM82187 |
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| n/a |
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| Name | BDBM82187 |
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| Synonyms: | Salicylic acid derivative, 76D10 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H18O9 |
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| Mol. Mass. | 486.4264 |
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| SMILES | OC(=O)c1cc(ccc1O)-c1ccc(\C=C\C(=O)\C=C\c2ccc(o2)-c2ccc(O)c(c2)C(O)=O)o1 |
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| Structure | 
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