Reaction Details |
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Target | GABA(A) receptor-associated protein |
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Ligand | BDBM50019260 |
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Substrate/Competitor | n/a |
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Ki | 3000±n/a nM |
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Comments | PDSP_45 |
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Citation | Evans, BE; Bock, MG; Rittle, KE; DiPardo, RM; Whitter, WL; Veber, DF; Anderson, PS; Freidinger, RM Design of potent, orally effective, nonpeptidal antagonists of the peptide hormone cholecystokinin. Proc Natl Acad Sci U S A83:4918-22 (1986) [PubMed] Article |
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More Info.: | Get all data from this article |
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GABA(A) receptor-associated protein |
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Name: | GABA(A) receptor-associated protein |
Synonyms: | GABA A Benzodiazepine | GABA-A receptor subunit alpha 1 |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 13921.89 |
Organism: | GUINEA PIG |
Description: | D7RA28 |
Residue: | 117 |
Sequence: | MKFVYKEEHPFEKRRSEGEKIRKKYPDRVPVIVEKAPKARIGDLDKKKYLVPSDLTVGQF
YFLIRKRIHLRAEDALFFFVNNVIPPTSATMGQLYQEHHEEDFFLYIAYSDESVYGL
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BDBM50019260 |
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n/a |
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Name | BDBM50019260 |
Synonyms: | 1H-Indole-2-carboxylic acid [5-(2-fluoro-phenyl)-2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl]-amide | 1H-Indole-2-carboxylic acid [5-(2-fluoro-phenyl)-2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl]-amide: 0.16CH2Cl2 | CCK antagonist synthetic 21 | CHEMBL306806 |
Type | Small organic molecule |
Emp. Form. | C24H17FN4O2 |
Mol. Mass. | 412.4158 |
SMILES | Fc1ccccc1C1=NC(NC(=O)c2cc3ccccc3[nH]2)C(=O)Nc2ccccc12 |t:8| |
Structure |
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