| Reaction Details |
|---|
 | Report a problem with these data |
| Target | D(4) dopamine receptor |
|---|
| Ligand | BDBM81777 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | 120.2±n/a nM |
|---|
| Comments | PDSP_1366 |
|---|
| Citation |  Lahti, RA; Evans, DL; Stratman, NC; Figur, LM Dopamine D4 versus D2 receptor selectivity of dopamine receptor antagonists: possible therapeutic implications. Eur J Pharmacol236:483-6 (1993) [PubMed] Article |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| D(4) dopamine receptor |
|---|
| Name: | D(4) dopamine receptor |
|---|
| Synonyms: | D(2C) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | DRD4_HUMAN | Dopamine D4 receptor |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 48373.19 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P21917 |
|---|
| Residue: | 419 |
|---|
| Sequence: | MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVA
TERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCT
ASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGR
DPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSG
PGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPG
LPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWT
PFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
|
|
|
|---|
| BDBM81777 |
|---|
| n/a |
|---|
| Name | BDBM81777 |
|---|
| Synonyms: | CAS_132-66-1 | NPA | NPA,(+) | NPA,(-) | NSC_8594 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H13NO3 |
|---|
| Mol. Mass. | 291.3007 |
|---|
| SMILES | OC(=O)c1ccccc1C(=O)Nc1cccc2ccccc12 |
|---|
| Structure | 
|
|---|
Search and Browse
