Reaction Details |
| Report a problem with these data |
Target | Delta-type opioid receptor |
---|
Ligand | BDBM50045216 |
---|
Substrate/Competitor | n/a |
---|
Ki | 1.7±n/a nM |
---|
Comments | PDSP_1713 |
---|
Citation | Raynor, K; Kong, H; Chen, Y; Yasuda, K; Yu, L; Bell, GI; Reisine, T Pharmacological characterization of the cloned kappa-, delta-, and mu-opioid receptors. Mol Pharmacol45:330-4 (1994) [PubMed] Article |
---|
More Info.: | Get all data from this article |
---|
|
Delta-type opioid receptor |
---|
Name: | Delta-type opioid receptor |
Synonyms: | D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1 |
Type: | G Protein-Coupled Receptor (GPCR) |
Mol. Mass.: | 40382.98 |
Organism: | Homo sapiens (Human) |
Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor. |
Residue: | 372 |
Sequence: | MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
|
|
|
BDBM50045216 |
---|
n/a |
---|
Name | BDBM50045216 |
Synonyms: | 7-(Spiroindano)Oxymorphone | 7-spiroindanyloxymorphone | SIOM |
Type | Small organic molecule |
Emp. Form. | C25H25NO4 |
Mol. Mass. | 403.4703 |
SMILES | CN1CC[C@@]23[C@H]4Oc5c2c(CC1[C@]3(O)CC1(Cc2ccccc2C1)C4=O)ccc5O |TLB:26:9:12:1.3.2,7:8:12:1.3.2| |
Structure |
|