| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 |
|---|
| Ligand | BDBM80289 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Dose Response confirmation of uHTS hits for Scp-1 phosphatase using a colorimetric assay |
|---|
| IC50 | 1734±109 nM |
|---|
| Citation |  PubChem, PC Dose Response confirmation of uHTS hits for Scp-1 phosphatase using a colorimetric assay PubChem Bioassay(2011)[AID] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 |
|---|
| Name: | Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 |
|---|
| Synonyms: | CTDS1_HUMAN | CTDSP1 | NIF3 | NLIIF | SCP1 | carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 1 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 29199.89 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | gi_10864009 |
|---|
| Residue: | 261 |
|---|
| Sequence: | MDSSAVITQISKEEARGPLRGKGDQKSAASQKPRSRGILHSLFCCVCRDDGEALPAHSGA
PLLVEENGAIPKQTPVQYLLPEAKAQDSDKICVVIDLDETLVHSSFKPVNNADFIIPVEI
DGVVHQVYVLKRPHVDEFLQRMGELFECVLFTASLAKYADPVADLLDKWGAFRARLFRES
CVFHRGNYVKDLSRLGRDLRRVLILDNSPASYVFHPDNAVPVASWFDNMSDTELHDLLPF
FEQLSRVDDVYSVLRQPRPGS
|
|
|
|---|
| BDBM80289 |
|---|
| n/a |
|---|
| Name | BDBM80289 |
|---|
| Synonyms: | (8S)-3-(3-methacrylamidophenyl)-7-[(E)-pent-2-enoyl]-1-oxa-2,7-diazaspiro[4.4]non-2-ene-8-carboxamide | (8S)-3-[3-(2-methylprop-2-enoylamino)phenyl]-7-[(E)-pent-2-enoyl]-1-oxa-2,7-diazaspiro[4.4]non-2-ene-8-carboxamide | (8S)-3-[3-[(2-methyl-1-oxoprop-2-enyl)amino]phenyl]-7-[(E)-1-oxopent-2-enyl]-1-oxa-2,7-diazaspiro[4.4]non-2-ene-8-carboxamide | MLS000562001 | SMR000390637 | cid_16745457 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H26N4O4 |
|---|
| Mol. Mass. | 410.4662 |
|---|
| SMILES | CC\C=C\C(=O)N1CC2(C[C@H]1C(N)=O)CC(=NO2)c1cccc(NC(=O)C(C)=C)c1 |c:16| |
|---|
| Structure | 
|
|---|
Search and Browse
