| Reaction Details |
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 | Report a problem with these data |
| Target | Toll-like receptor 9 |
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| Ligand | BDBM53465 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Fluorescence-based cell-based high throughput dose response assay for inhibitors of TLR9-MyD88 binding |
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| IC50 | 3780±n/a nM |
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| Citation |  PubChem, PC Fluorescence-based cell-based high throughput dose response assay for inhibitors of TLR9-MyD88 binding PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| Toll-like receptor 9 |
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| Name: | Toll-like receptor 9 |
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| Synonyms: | CD_antigen: CD289 | TLR9 | TLR9_HUMAN |
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| Type: | Enzyme |
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| Mol. Mass.: | 115889.91 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9NR96 |
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| Residue: | 1032 |
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| Sequence: | MGFCRSALHPLSLLVQAIMLAMTLALGTLPAFLPCELQPHGLVNCNWLFLKSVPHFSMAA
PRGNVTSLSLSSNRIHHLHDSDFAHLPSLRHLNLKWNCPPVGLSPMHFPCHMTIEPSTFL
AVPTLEELNLSYNNIMTVPALPKSLISLSLSHTNILMLDSASLAGLHALRFLFMDGNCYY
KNPCRQALEVAPGALLGLGNLTHLSLKYNNLTVVPRNLPSSLEYLLLSYNRIVKLAPEDL
ANLTALRVLDVGGNCRRCDHAPNPCMECPRHFPQLHPDTFSHLSRLEGLVLKDSSLSWLN
ASWFRGLGNLRVLDLSENFLYKCITKTKAFQGLTQLRKLNLSFNYQKRVSFAHLSLAPSF
GSLVALKELDMHGIFFRSLDETTLRPLARLPMLQTLRLQMNFINQAQLGIFRAFPGLRYV
DLSDNRISGASELTATMGEADGGEKVWLQPGDLAPAPVDTPSSEDFRPNCSTLNFTLDLS
RNNLVTVQPEMFAQLSHLQCLRLSHNCISQAVNGSQFLPLTGLQVLDLSHNKLDLYHEHS
FTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTLRHLSLAHNNIHSQVSQQLCSTSL
RALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLSQNRLHTLLPQTLRNLPKSLQVLRL
RDNYLAFFKWWSLHFLPKLEVLDLAGNQLKALTNGSLPAGTRLRRLDVSCNSISFVAPGF
FSKAKELRELNLSANALKTVDHSWFGPLASALQILDVSANPLHCACGAAFMDFLLEVQAA
VPGLPSRVKCGSPGQLQGLSIFAQDLRLCLDEALSWDCFALSLLAVALGLGVPMLHHLCG
WDLWYCFHLCLAWLPWRGRQSGRDEDALPYDAFVVFDKTQSAVADWVYNELRGQLEECRG
RWALRLCLEERDWLPGKTLFENLWASVYGSRKTLFVLAHTDRVSGLLRASFLLAQQRLLE
DRKDVVVLVILSPDGRRSRYVRLRQRLCRQSVLLWPHQPSGQRSFWAQLGMALTRDNHHF
YNRNFCQGPTAE
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| BDBM53465 |
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| n/a |
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| Name | BDBM53465 |
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| Synonyms: | 3-(7-Chloro-4-nitro-benzo[1,2,5]oxadiazol-5-ylamino)-phenol | 3-[(7-chloranyl-4-nitro-2,1,3-benzoxadiazol-5-yl)amino]phenol | 3-[(7-chloro-4-nitro-2,1,3-benzoxadiazol-5-yl)amino]phenol | 3-[(7-chloro-4-nitro-benzofurazan-5-yl)amino]phenol | MLS001206676 | O-acyl oxime isatin derivative, 48 | SMR000516453 | cid_3128208 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H7ClN4O4 |
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| Mol. Mass. | 306.661 |
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| SMILES | Oc1cccc(Nc2cc(Cl)c3nonc3c2[N+]([O-])=O)c1 |
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| Structure | 
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