| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Apelin receptor |
|---|
| Ligand | BDBM80006 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | SAR analysis counterscreen of small molecule antagonists of the CCR6 receptor using an APJ receptor luminescent beta-arrestin assay |
|---|
| IC50 | 14800±n/a nM |
|---|
| Citation |  PubChem, PC SAR analysis counterscreen of small molecule antagonists of the CCR6 receptor using an APJ receptor luminescent beta-arrestin assay PubChem Bioassay(2011)[AID] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Apelin receptor |
|---|
| Name: | Apelin receptor |
|---|
| Synonyms: | AGTRL1 | APJ | APJ_HUMAN | APLNR | Angiotensin receptor-like 1 | Apelin receptor | Apelin receptor (APJ) | G-protein coupled receptor APJ | G-protein coupled receptor HG11 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 42664.06 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P35414 |
|---|
| Residue: | 380 |
|---|
| Sequence: | MEEGGDFDNYYGADNQSECEYTDWKSSGALIPAIYMLVFLLGTTGNGLVLWTVFRSSREK
RRSADIFIASLAVADLTFVVTLPLWATYTYRDYDWPFGTFFCKLSSYLIFVNMYASVFCL
TGLSFDRYLAIVRPVANARLRLRVSGAVATAVLWVLAALLAMPVMVLRTTGDLENTTKVQ
CYMDYSMVATVSSEWAWEVGLGVSSTTVGFVVPFTIMLTCYFFIAQTIAGHFRKERIEGL
RKRRRLLSIIVVLVVTFALCWMPYHLVKTLYMLGSLLHWPCDFDLFLMNIFPYCTCISYV
NSCLNPFLYAFFDPRFRQACTSMLCCGQSRCAGTSHSSSGEKSASYSSGHSQGPGPNMGK
GGEQMHEKSIPYSQETLVVD
|
|
|
|---|
| BDBM80006 |
|---|
| n/a |
|---|
| Name | BDBM80006 |
|---|
| Synonyms: | 2,5-diphenyl-N'-(phenylcarbonyl)pyrazole-3-carbohydrazide | MLS000388665 | N'-benzoyl-2,5-diphenyl-3-pyrazolecarbohydrazide | N'-benzoyl-2,5-diphenyl-pyrazole-3-carbohydrazide | N'-benzoyl-2,5-diphenylpyrazole-3-carbohydrazide | SMR000254838 | cid_4883406 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H18N4O2 |
|---|
| Mol. Mass. | 382.4146 |
|---|
| SMILES | O=C(NNC(=O)c1ccccc1)c1cc(nn1-c1ccccc1)-c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
