| Reaction Details |
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 | Report a problem with these data |
| Target | Apelin receptor |
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| Ligand | BDBM80072 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | SAR analysis counterscreen of small molecule antagonists of the CCR6 receptor using an APJ receptor luminescent beta-arrestin assay |
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| IC50 | 4120±n/a nM |
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| Citation |  PubChem, PC SAR analysis counterscreen of small molecule antagonists of the CCR6 receptor using an APJ receptor luminescent beta-arrestin assay PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| Apelin receptor |
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| Name: | Apelin receptor |
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| Synonyms: | AGTRL1 | APJ | APJ_HUMAN | APLNR | Angiotensin receptor-like 1 | Apelin receptor | Apelin receptor (APJ) | G-protein coupled receptor APJ | G-protein coupled receptor HG11 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 42664.06 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P35414 |
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| Residue: | 380 |
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| Sequence: | MEEGGDFDNYYGADNQSECEYTDWKSSGALIPAIYMLVFLLGTTGNGLVLWTVFRSSREK
RRSADIFIASLAVADLTFVVTLPLWATYTYRDYDWPFGTFFCKLSSYLIFVNMYASVFCL
TGLSFDRYLAIVRPVANARLRLRVSGAVATAVLWVLAALLAMPVMVLRTTGDLENTTKVQ
CYMDYSMVATVSSEWAWEVGLGVSSTTVGFVVPFTIMLTCYFFIAQTIAGHFRKERIEGL
RKRRRLLSIIVVLVVTFALCWMPYHLVKTLYMLGSLLHWPCDFDLFLMNIFPYCTCISYV
NSCLNPFLYAFFDPRFRQACTSMLCCGQSRCAGTSHSSSGEKSASYSSGHSQGPGPNMGK
GGEQMHEKSIPYSQETLVVD
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| BDBM80072 |
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| n/a |
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| Name | BDBM80072 |
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| Synonyms: | (6E)-6-[1-(2-quinolin-2-ylhydrazinyl)ethylidene]cyclohexa-2,4-dien-1-one | (6E)-6-[1-(2-quinolinylhydrazo)ethylidene]-1-cyclohexa-2,4-dienone | (6E)-6-[1-[N'-(2-quinolyl)hydrazino]ethylidene]cyclohexa-2,4-dien-1-one | (6Z)-6-[1-[N''-(2-quinolyl)hydrazino]ethylidene]cyclohexa-2,4-dien-1-one | (6Z)-6-[1-[N'-(2-quinolyl)hydrazino]ethylidene]cyclohexa-2,4-dien-1-one | MLS002702053 | SMR001565625 | cid_5383429 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H15N3O |
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| Mol. Mass. | 277.3205 |
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| SMILES | CC(N=Nc1ccc2ccccc2n1)c1ccccc1O |w:2.1| |
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| Structure | 
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