| Reaction Details |
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 | Report a problem with these data |
| Target | Apelin receptor |
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| Ligand | BDBM72680 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | SAR analysis counterscreen of small molecule antagonists of the CCR6 receptor using an APJ receptor luminescent beta-arrestin assay |
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| IC50 | 7220±n/a nM |
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| Citation |  PubChem, PC SAR analysis counterscreen of small molecule antagonists of the CCR6 receptor using an APJ receptor luminescent beta-arrestin assay PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| Apelin receptor |
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| Name: | Apelin receptor |
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| Synonyms: | AGTRL1 | APJ | APJ_HUMAN | APLNR | Angiotensin receptor-like 1 | Apelin receptor | Apelin receptor (APJ) | G-protein coupled receptor APJ | G-protein coupled receptor HG11 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 42664.06 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P35414 |
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| Residue: | 380 |
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| Sequence: | MEEGGDFDNYYGADNQSECEYTDWKSSGALIPAIYMLVFLLGTTGNGLVLWTVFRSSREK
RRSADIFIASLAVADLTFVVTLPLWATYTYRDYDWPFGTFFCKLSSYLIFVNMYASVFCL
TGLSFDRYLAIVRPVANARLRLRVSGAVATAVLWVLAALLAMPVMVLRTTGDLENTTKVQ
CYMDYSMVATVSSEWAWEVGLGVSSTTVGFVVPFTIMLTCYFFIAQTIAGHFRKERIEGL
RKRRRLLSIIVVLVVTFALCWMPYHLVKTLYMLGSLLHWPCDFDLFLMNIFPYCTCISYV
NSCLNPFLYAFFDPRFRQACTSMLCCGQSRCAGTSHSSSGEKSASYSSGHSQGPGPNMGK
GGEQMHEKSIPYSQETLVVD
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| BDBM72680 |
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| n/a |
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| Name | BDBM72680 |
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| Synonyms: | 5-[5-(4-Chloro-phenyl)-pyrazolidin-3-ylidene]-1,3-dimethyl-pyrimidine-2,4,6-trione | 5-[5-(4-chlorophenyl)-3-pyrazolidinylidene]-1,3-dimethyl-1,3-diazinane-2,4,6-trione | 5-[5-(4-chlorophenyl)pyrazolidin-3-ylidene]-1,3-dimethyl-1,3-diazinane-2,4,6-trione | 5-[5-(4-chlorophenyl)pyrazolidin-3-ylidene]-1,3-dimethyl-barbituric acid | MLS000762999 | SMR000439471 | cid_6224486 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H15ClN4O3 |
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| Mol. Mass. | 334.758 |
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| SMILES | CN1C(=O)C(C2CC(N=N2)c2ccc(Cl)cc2)C(=O)N(C)C1=O |c:8| |
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| Structure | 
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