| Reaction Details |
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 | Report a problem with these data |
| Target | Phospholipase A2 |
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| Ligand | BDBM80861 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose response counterscreen of uHTS hits for ATG4B inhibitors in a Phospholipase A2 assay |
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| IC50 | 182±n/a nM |
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| Citation |  PubChem, PC Dose response counterscreen of uHTS hits for ATG4B inhibitors in a Phospholipase A2 assay PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| Phospholipase A2 |
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| Name: | Phospholipase A2 |
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| Synonyms: | Group IB phospholipase A2 | PA21B_HUMAN | PLA2 | PLA2A | PLA2G1B | PPLA2 | Phosphatidylcholine 2-acylhydrolase 1B | Phospholipase A2 (PLA2) | Phospholipase A2 group 1B | phospholipase A2 precursor |
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| Type: | Protein |
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| Mol. Mass.: | 16364.13 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P04054 |
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| Residue: | 148 |
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| Sequence: | MKLLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGTPV
DELDKCCQTHDNCYDQAKKLDSCKFLLDNPYTHTYSYSCSGSAITCSSKNKECEAFICNC
DRNAAICFSKAPYNKAHKNLDTKKYCQS
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| BDBM80861 |
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| n/a |
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| Name | BDBM80861 |
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| Synonyms: | 4-[2-(2-Cyclohexyl-5,6-dimethyl-thieno[2,3-d]pyrimidin-4-ylsulfanyl)-acetyl]-3,4-dihydro-1H-quinoxalin-2-one | 4-[2-(2-cyclohexyl-5,6-dimethyl-thieno[2,3-d]pyrimidin-4-yl)sulfanylethanoyl]-1,3-dihydroquinoxalin-2-one | 4-[2-(2-cyclohexyl-5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)sulfanylacetyl]-1,3-dihydroquinoxalin-2-one | 4-[2-[(2-cyclohexyl-5,6-dimethyl-4-thieno[2,3-d]pyrimidinyl)thio]-1-oxoethyl]-1,3-dihydroquinoxalin-2-one | 4-[2-[(2-cyclohexyl-5,6-dimethyl-thieno[2,3-d]pyrimidin-4-yl)thio]acetyl]-1,3-dihydroquinoxalin-2-one | MLS000555707 | SMR000173088 | cid_3203918 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H26N4O2S2 |
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| Mol. Mass. | 466.619 |
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| SMILES | Cc1sc2nc(nc(SCC(=O)N3CC(=O)Nc4ccccc34)c2c1C)C1CCCCC1 |
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| Structure | 
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