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TargetPhospholipase A2
LigandBDBM80864
Substrate/Competitorn/a
Meas. Tech.Dose response counterscreen of uHTS hits for ATG4B inhibitors in a Phospholipase A2 assay
IC50 2830±n/a nM
Citation PubChem, PC Dose response counterscreen of uHTS hits for ATG4B inhibitors in a Phospholipase A2 assay PubChem Bioassay(2011)[AID]
More Info.:Get all data from this article,  Assay Method
 
Phospholipase A2
Name:Phospholipase A2
Synonyms:Group IB phospholipase A2 | PA21B_HUMAN | PLA2 | PLA2A | PLA2G1B | PPLA2 | Phosphatidylcholine 2-acylhydrolase 1B | Phospholipase A2 (PLA2) | Phospholipase A2 group 1B | phospholipase A2 precursor
Type:Protein
Mol. Mass.:16364.13
Organism:Homo sapiens (Human)
Description:P04054
Residue:148
Sequence:
MKLLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGTPV
DELDKCCQTHDNCYDQAKKLDSCKFLLDNPYTHTYSYSCSGSAITCSSKNKECEAFICNC
DRNAAICFSKAPYNKAHKNLDTKKYCQS
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  Blast E-value cutoff:
BDBM80864
n/a
NameBDBM80864
Synonyms:(3,4-dihydro-2H-naphthalen-1-ylideneamino) 4-methylbenzoate | 1-{[(4-methylbenzoyl)oxy]imino}-1,2,3,4-tetrahydronaphthalene | 4-methylbenzoic acid (3,4-dihydro-2H-naphthalen-1-ylideneamino) ester | 4-methylbenzoic acid (tetralin-1-ylideneamino) ester | MLS000546835 | SMR000180033 | cid_2766061
TypeSmall organic molecule
Emp. Form.C18H17NO2
Mol. Mass.279.3331
SMILESCc1ccc(cc1)C(=O)ON=C1CCCc2ccccc12
Structure
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