Reaction Details |
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Target | Phospholipase A2 |
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Ligand | BDBM57436 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose response counterscreen of uHTS hits for ATG4B inhibitors in a Phospholipase A2 assay |
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IC50 | 3240±n/a nM |
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Citation | PubChem, PC Dose response counterscreen of uHTS hits for ATG4B inhibitors in a Phospholipase A2 assay PubChem Bioassay(2011)[AID] |
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More Info.: | Get all data from this article, Assay Method |
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Phospholipase A2 |
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Name: | Phospholipase A2 |
Synonyms: | Group IB phospholipase A2 | PA21B_HUMAN | PLA2 | PLA2A | PLA2G1B | PPLA2 | Phosphatidylcholine 2-acylhydrolase 1B | Phospholipase A2 (PLA2) | Phospholipase A2 group 1B | phospholipase A2 precursor |
Type: | Protein |
Mol. Mass.: | 16364.13 |
Organism: | Homo sapiens (Human) |
Description: | P04054 |
Residue: | 148 |
Sequence: | MKLLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGTPV
DELDKCCQTHDNCYDQAKKLDSCKFLLDNPYTHTYSYSCSGSAITCSSKNKECEAFICNC
DRNAAICFSKAPYNKAHKNLDTKKYCQS
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BDBM57436 |
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n/a |
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Name | BDBM57436 |
Synonyms: | 1-[2-[(3,4-dichlorobenzyl)thio]ethyl]-3-phenyl-thiourea | 1-[2-[(3,4-dichlorophenyl)methylsulfanyl]ethyl]-3-phenyl-thiourea | 1-[2-[(3,4-dichlorophenyl)methylsulfanyl]ethyl]-3-phenylthiourea | 1-[2-[(3,4-dichlorophenyl)methylthio]ethyl]-3-phenylthiourea | MLS000575256 | N-{2-[(3,4-dichlorobenzyl)thio]ethyl}-N'-phenylthiourea | SMR000196491 | cid_2290454 |
Type | Small organic molecule |
Emp. Form. | C16H16Cl2N2S2 |
Mol. Mass. | 371.348 |
SMILES | Clc1ccc(CSCCNC(=S)Nc2ccccc2)cc1Cl |
Structure |
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