| Reaction Details |
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 | Report a problem with these data |
| Target | Phospholipase A2 |
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| Ligand | BDBM80876 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose response counterscreen of uHTS hits for ATG4B inhibitors in a Phospholipase A2 assay |
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| IC50 | 2530±n/a nM |
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| Citation |  PubChem, PC Dose response counterscreen of uHTS hits for ATG4B inhibitors in a Phospholipase A2 assay PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| Phospholipase A2 |
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| Name: | Phospholipase A2 |
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| Synonyms: | Group IB phospholipase A2 | PA21B_HUMAN | PLA2 | PLA2A | PLA2G1B | PPLA2 | Phosphatidylcholine 2-acylhydrolase 1B | Phospholipase A2 (PLA2) | Phospholipase A2 group 1B | phospholipase A2 precursor |
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| Type: | Protein |
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| Mol. Mass.: | 16364.13 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P04054 |
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| Residue: | 148 |
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| Sequence: | MKLLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGTPV
DELDKCCQTHDNCYDQAKKLDSCKFLLDNPYTHTYSYSCSGSAITCSSKNKECEAFICNC
DRNAAICFSKAPYNKAHKNLDTKKYCQS
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| BDBM80876 |
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| n/a |
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| Name | BDBM80876 |
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| Synonyms: | (4-Oxo-3-p-tolyl-3,4-dihydro-quinazolin-2-ylsulfanyl)-acetic acid [(E)-3-(2-nitro-phenyl)-prop-2-en-(E)-ylidene]-hydrazide | 2-[3-(4-methylphenyl)-4-oxidanylidene-quinazolin-2-yl]sulfanyl-N-[[(E)-3-(2-nitrophenyl)prop-2-enylidene]amino]ethanamide | 2-[3-(4-methylphenyl)-4-oxoquinazolin-2-yl]sulfanyl-N-[[(E)-3-(2-nitrophenyl)prop-2-enylidene]amino]acetamide | 2-[[3-(4-methylphenyl)-4-oxo-2-quinazolinyl]thio]-N-[[(E)-3-(2-nitrophenyl)prop-2-enylidene]amino]acetamide | 2-[[4-keto-3-(p-tolyl)quinazolin-2-yl]thio]-N-[[(E)-3-(2-nitrophenyl)prop-2-enylidene]amino]acetamide | MLS000590981 | SMR000217775 | cid_12004498 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H21N5O4S |
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| Mol. Mass. | 499.541 |
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| SMILES | Cc1ccc(cc1)-n1c(SCC(=O)N\N=C\C=C\c2ccccc2[N+]([O-])=O)nc2ccccc2c1=O |
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| Structure | 
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