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Reaction Details
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TargetPhospholipase A2
LigandBDBM42535
Substrate/Competitorn/a
Meas. Tech.Dose response counterscreen of uHTS hits for ATG4B inhibitors in a Phospholipase A2 assay
IC50 4740±n/a nM
Citation PubChem, PC Dose response counterscreen of uHTS hits for ATG4B inhibitors in a Phospholipase A2 assay PubChem Bioassay(2011)[AID]
More Info.:Get all data from this article,  Assay Method
 
Phospholipase A2
Name:Phospholipase A2
Synonyms:Group IB phospholipase A2 | PA21B_HUMAN | PLA2 | PLA2A | PLA2G1B | PPLA2 | Phosphatidylcholine 2-acylhydrolase 1B | Phospholipase A2 (PLA2) | Phospholipase A2 group 1B | phospholipase A2 precursor
Type:Protein
Mol. Mass.:16364.13
Organism:Homo sapiens (Human)
Description:P04054
Residue:148
Sequence:
MKLLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGTPV
DELDKCCQTHDNCYDQAKKLDSCKFLLDNPYTHTYSYSCSGSAITCSSKNKECEAFICNC
DRNAAICFSKAPYNKAHKNLDTKKYCQS
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  Blast E-value cutoff:
BDBM42535
n/a
NameBDBM42535
Synonyms:2-(4-chlorophenyl)sulfanyl-N-(2-phenylphenyl)propanamide | 2-[(4-chlorophenyl)thio]-N-(2-phenylphenyl)propanamide | 2-[(4-chlorophenyl)thio]-N-(2-phenylphenyl)propionamide | MLS000578917 | N-2-biphenylyl-2-[(4-chlorophenyl)thio]propanamide | SMR000198737 | cid_2942743
TypeSmall organic molecule
Emp. Form.C21H18ClNOS
Mol. Mass.367.892
SMILESCC(Sc1ccc(Cl)cc1)C(=O)Nc1ccccc1-c1ccccc1
Structure
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