Ki Summary

Reaction Details

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Target

Phospholipase A2

Ligand

BDBM47026

Substrate/Competitor

n/a

Meas. Tech.

Dose response counterscreen of uHTS hits for ATG4B inhibitors in a Phospholipase A2 assay

IC50

2040±n/a nM

Citation

PubChem, PC Dose response counterscreen of uHTS hits for ATG4B inhibitors in a Phospholipase A2 assay PubChem Bioassay(2011)[AID]

More Info.:

Get all data from this article, Assay Method

Phospholipase A2

Name:

Phospholipase A2

Synonyms:

Type:

Protein

Mol. Mass.:

16364.13

Organism:

Homo sapiens (Human)

Description:

P04054

Residue:

148

Sequence:

MKLLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGTPV
DELDKCCQTHDNCYDQAKKLDSCKFLLDNPYTHTYSYSCSGSAITCSSKNKECEAFICNC
DRNAAICFSKAPYNKAHKNLDTKKYCQS

BDBM47026

n/a

Name

BDBM47026

Synonyms:

(Z)-2-methyl-6-[(5R,10S,13R,14R,17R)-4,4,10,13,14-pentamethyl-3-oxidanylidene-1,2,5,6,7,11,12,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]hept-2-enoic acid | (Z)-2-methyl-6-[(5R,10S,13R,14R,17R)-4,4,10,13,14-pentamethyl-3-oxo-1,2,5,6,7,11,12,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]-2-heptenoic acid | (Z)-2-methyl-6-[(5R,10S,13R,14R,17R)-4,4,10,13,14-pentamethyl-3-oxo-1,2,5,6,7,11,12,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]hept-2-enoic acid | (Z)-6-[(5R,10S,13R,14R,17R)-3-keto-4,4,10,13,14-pentamethyl-1,2,5,6,7,11,12,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]-2-methyl-hept-2-enoic acid | MLS000563429 | SMR000232277 | cid_15944767

Type

Small organic molecule

Emp. Form.

C30H46O3

Mol. Mass.

454.6844

SMILES

CC(CC\C=C(\C)C(O)=O)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]1(C)CCC(=O)C(C)(C)[C@@H]1CC3 |c:15|

Structure