| Reaction Details |
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 | Report a problem with these data |
| Target | Endoribonuclease toxin MazF |
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| Ligand | BDBM30698 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay |
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| EC50 | >99000±n/a nM |
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| Citation |  PubChem, PC Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| Endoribonuclease toxin MazF |
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| Name: | Endoribonuclease toxin MazF |
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| Synonyms: | MAZF_ECOLI | chpA | chpAK | mRNA interferase toxin, antitoxin is MazE | mazF |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 12100.43 |
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| Organism: | Escherichia coli str. K-12 substr. MG1655 |
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| Description: | gi_16130689 |
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| Residue: | 111 |
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| Sequence: | MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPF
EVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
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| BDBM30698 |
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| n/a |
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| Name | BDBM30698 |
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| Synonyms: | 2-(2,4-dimethoxyanilino)-7-keto-N-(tetrahydrofurfuryl)chromene-3-carboxamide | 2-(2,4-dimethoxyanilino)-7-oxo-N-(2-oxolanylmethyl)-1-benzopyran-3-carboxamide | 2-(2,4-dimethoxyanilino)-7-oxo-N-(oxolan-2-ylmethyl)chromene-3-carboxamide | 2-[(2,4-dimethoxyphenyl)amino]-7-oxidanylidene-N-(oxolan-2-ylmethyl)chromene-3-carboxamide | 2-[(Z)-2,4-Dimethoxy-phenylimino]-7-hydroxy-2H-chromene-3-carboxylic acid (tetrahydro-furan-2-ylmethyl)-amide | MLS000072508 | SMR000002220 | cid_656123 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H24N2O6 |
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| Mol. Mass. | 424.4465 |
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| SMILES | COc1ccc(Nc2oc3cc(=O)ccc3cc2C(=O)NCC2CCCO2)c(OC)c1 |
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| Structure | 
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