| Reaction Details |
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 | Report a problem with these data |
| Target | Endoribonuclease toxin MazF |
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| Ligand | BDBM46749 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay |
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| EC50 | >99000±n/a nM |
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| Citation |  PubChem, PC Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| Endoribonuclease toxin MazF |
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| Name: | Endoribonuclease toxin MazF |
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| Synonyms: | MAZF_ECOLI | chpA | chpAK | mRNA interferase toxin, antitoxin is MazE | mazF |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 12100.43 |
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| Organism: | Escherichia coli str. K-12 substr. MG1655 |
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| Description: | gi_16130689 |
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| Residue: | 111 |
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| Sequence: | MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPF
EVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
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| BDBM46749 |
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| n/a |
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| Name | BDBM46749 |
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| Synonyms: | 1-acetyl-3-(2,6-dimethyl-4-pyranylidene)-2-indolone | 1-acetyl-3-(2,6-dimethyl-4H-pyran-4-ylidene)-1,3-dihydro-2H-indol-2-one | 1-acetyl-3-(2,6-dimethylpyran-4-ylidene)indol-2-one | 1-acetyl-3-(2,6-dimethylpyran-4-ylidene)oxindole | 3-(2,6-dimethylpyran-4-ylidene)-1-ethanoyl-indol-2-one | MLS000043288 | SMR000019908 | cid_697318 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H15NO3 |
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| Mol. Mass. | 281.3059 |
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| SMILES | [#6]-[#6](=O)-[#7]-1-[#6](=O)\[#6](-c2ccccc-12)=[#6]-1\[#6]=[#6](-[#6])-[#8]-[#6](-[#6])=[#6]-1 |c:21,t:16| |
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| Structure | 
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