| Reaction Details |
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 | Report a problem with these data |
| Target | Endoribonuclease toxin MazF |
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| Ligand | BDBM83484 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay |
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| EC50 | >99000±n/a nM |
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| Citation |  PubChem, PC Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| Endoribonuclease toxin MazF |
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| Name: | Endoribonuclease toxin MazF |
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| Synonyms: | MAZF_ECOLI | chpA | chpAK | mRNA interferase toxin, antitoxin is MazE | mazF |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 12100.43 |
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| Organism: | Escherichia coli str. K-12 substr. MG1655 |
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| Description: | gi_16130689 |
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| Residue: | 111 |
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| Sequence: | MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPF
EVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
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| BDBM83484 |
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| n/a |
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| Name | BDBM83484 |
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| Synonyms: | 5-[[3-(3,5-dimethyl-1-pyrazolyl)-2-quinoxalinyl]amino]-1,3-dihydrobenzimidazol-2-one | 5-[[3-(3,5-dimethylpyrazol-1-yl)quinoxalin-2-yl]amino]-1,3-dihydrobenzimidazol-2-one | 5-{[3-(3,5-dimethyl-1H-pyrazol-1-yl)-2-quinoxalinyl]amino}-1,3-dihydro-2H-benzimidazol-2-one | MLS000052022 | SMR000081300 | cid_1250673 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H17N7O |
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| Mol. Mass. | 371.3953 |
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| SMILES | Cc1cc(C)n(n1)-c1nc2ccccc2nc1Nc1ccc2[nH]c(=O)[nH]c2c1 |
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| Structure | 
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