| Reaction Details |
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 | Report a problem with these data |
| Target | Endoribonuclease toxin MazF |
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| Ligand | BDBM83469 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay counterscreen |
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| EC50 | >99000±n/a nM |
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| Citation |  PubChem, PC Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay counterscreen PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| Endoribonuclease toxin MazF |
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| Name: | Endoribonuclease toxin MazF |
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| Synonyms: | MAZF_ECOLI | chpA | chpAK | mRNA interferase toxin, antitoxin is MazE | mazF |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 12100.43 |
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| Organism: | Escherichia coli str. K-12 substr. MG1655 |
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| Description: | gi_16130689 |
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| Residue: | 111 |
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| Sequence: | MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPF
EVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
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| BDBM83469 |
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| n/a |
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| Name | BDBM83469 |
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| Synonyms: | (5Z)-3-ethyl-5-(1-ethyl-2-quinolinylidene)-2-sulfanylidene-4-oxazolidinone | (5Z)-3-ethyl-5-(1-ethyl-2-quinolylidene)-2-thioxo-oxazolidin-4-one | (5Z)-3-ethyl-5-(1-ethylquinolin-2-ylidene)-2-sulfanylidene-1,3-oxazolidin-4-one | 3-Ethyl-5-[1-ethyl-1H-quinolin-(2Z)-ylidene]-2-thioxo-oxazolidin-4-one | MLS000068950 | SMR000008534 | cid_3098234 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H16N2O2S |
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| Mol. Mass. | 300.375 |
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| SMILES | CCN1C(=S)O\C(C1=O)=C1\C=Cc2ccccc2N1CC |c:11| |
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| Structure | 
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