Reaction Details |
![](/images/Email.png) | Report a problem with these data |
Target | Endoribonuclease toxin MazF |
---|
Ligand | BDBM83473 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay counterscreen |
---|
EC50 | >99000±n/a nM |
---|
Citation | PubChem, PC Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay counterscreen PubChem Bioassay(2011)[AID] |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
Endoribonuclease toxin MazF |
---|
Name: | Endoribonuclease toxin MazF |
Synonyms: | MAZF_ECOLI | chpA | chpAK | mRNA interferase toxin, antitoxin is MazE | mazF |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 12100.43 |
Organism: | Escherichia coli str. K-12 substr. MG1655 |
Description: | gi_16130689 |
Residue: | 111 |
Sequence: | MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPF
EVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
|
|
|
BDBM83473 |
---|
n/a |
---|
Name | BDBM83473 |
Synonyms: | 4-[5-(3-methoxyphenyl)-1,7-dihydro-[1,2,3,4]tetrazolo[1,5-a]pyrimidin-7-yl]-N,N-dimethyl-aniline | 4-[5-(3-methoxyphenyl)-1,7-dihydrotetrazolo[1,5-a]pyrimidin-7-yl]-N,N-dimethylaniline | MLS000077686 | SMR000035047 | [4-[5-(3-methoxyphenyl)-1,7-dihydrotetrazolo[1,5-a]pyrimidin-7-yl]phenyl]-dimethyl-amine | cid_5389474 |
Type | Small organic molecule |
Emp. Form. | C19H20N6O |
Mol. Mass. | 348.4017 |
SMILES | COc1cccc(c1)C1=Nc2nnnn2C(C1)c1ccc(cc1)N(C)C |t:9| |
Structure |
|