| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Multidrug resistance protein CDR2 |
|---|
| Ligand | BDBM84112 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Dose Response HTS singleplex for inhibitors of yeast efflux pump, specifically Cdr2 with Hit compounds from Cherry Pick1 |
|---|
| EC50 | 1530±n/a nM |
|---|
| Citation |  PubChem, PC Dose Response HTS singleplex for inhibitors of yeast efflux pump, specifically Cdr2 with Hit compounds from Cherry Pick1 PubChem Bioassay(2011)[AID] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Multidrug resistance protein CDR2 |
|---|
| Name: | Multidrug resistance protein CDR2 |
|---|
| Synonyms: | CDR2 | CDR2_CANAL | drug resistance protein 2 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 168970.05 |
|---|
| Organism: | Candida albicans |
|---|
| Description: | P78595 |
|---|
| Residue: | 1499 |
|---|
| Sequence: | MSTANTSLSQQLDEKPWVDASDNSSVQEYQGFDATASHNIQDLARKLTHGSTNGDHHSAN
DLARYLSHMSDIPGVSPFNGNISHEQLDPDSENFNAKYWVKNLKKLFESDSDYYKPSKLG
VAYRNLRAYGIANDSDYQPTVTNALWKFTTEAINKLKKPDDSKYFDILKSMDAIMRPGEL
TVVLGRPGAGCSTLLKTIAVNTYGFHIGKESQITYDGLSPHDIERHYRGDVIYSAETDVH
FPHLSVGDTLEFAARLRTPQNRGEGIDRETYAKHMASVYMATYGLSHTRNTNVGNDFVRG
VSGGERKRVSIAEASLSGANIQCWDNATRGLDSATALEFIRALKTSATILDTTPLIAIYQ
CSQDAYELFDNVVVLYEGYQIFFGKASKAKEYFENMGWKCPQRQTTADFLTSLTNPAERE
PLPGYEDKVPRTAQEFETFWKNSPEYAELTKEIDEYFVECERSNTGETYRESHVAKQSNN
TRPSSPYTVSFFMQVRYVIARNFLRMKGDPSIPLISILSQLVMGLILASVFFNLRKSTDT
FYFRGGALFFSVLFNAFSSLLEILSLYEARPIVEKHRKYALYRPSADALASIISELPVKL
LMTMSFNIVYYFMVNLRRTAGNFFFYWLMCASCTLVMSHMFRSIGAVTTTIATAMSLSTV
FLLAMIIYAGFVLPIPYILGWSRWIRYINPVTYIFESLMVNEFHGREFECGQYIPSGPGF
ENLPVENKVCTTVGSTPGSTVVQGTEYIKLAYQFYSSHKWRNFGITVAFAVFFLGVYVAL
TEFNKGAMQKGEIVLFLKGSLKKHKRKTAASNKGDIEAGPVAGKLDYQDEAEAVNNEKFT
EKGSTGSVDFPENREIFFWRDLTYQVKIKKEDRVILDHVDGWVKPGQITALMGASGAGKT
TLLNCLSERVTTGIITDGERLVNGHALDSSFQRSIGYVQQQDVHLETTTVREALQFSAYL
RQSNKISKKEKDDYVDYVIDLLEMTDYADALVGVAGEGLNVEQRKRLTIGVELVAKPKLL
LFLDEPTSGLDSQTAWSICKLMRKLADHGQAILCTIHQPSALIMAEFDKLLFLQKGGRTA
YFGELGENCQTMINYFEKYGADPCPKEANPAEWMLQVVGAAPGSHAKQDYFEVWRNSSEY
QAVREEINRMEAELSKLPRDNDPEALLKYAAPLWKQYLLVSWRTIVQDWRSPGYIYSKLI
LVISSSLFIGFSFFKSKNNLQGLQSQMLAVFMFFVPFTTFIDQMLPYFVKHRAVYEVREA
PSRTFSWFAFIAGQITSEIPFQIVVGTISYFCWYYPVGLYANAEPTDSVNSRGVLMWMLL
TAFYVYTSTMGQLAISLNELIDNAANLATTLFTLCLMFCGVLAGPNVIPGFWIFMYRCNP
FTYLIQAILSTGLANAKVTCAPRELVTLKPPMGETCSSFIGPYTEAAGGYFSTNSDGTCS
VCRIDSTNQFLESINALFSQRWRNFGIFVAFIGINIILTIFFYWLARVPKGNREKKMKK
|
|
|
|---|
| BDBM84112 |
|---|
| n/a |
|---|
| Name | BDBM84112 |
|---|
| Synonyms: | MLS000554997 | N-Benzooxazol-2-yl-N',N''-dibenzoyl-guanidine | N-[N'-(1,3-benzoxazol-2-yl)-N-(phenylcarbonyl)carbamimidoyl]benzamide | N-[N'-(1,3-benzoxazol-2-yl)-N-benzoyl-amidino]benzamide | N-[N'-(1,3-benzoxazol-2-yl)-N-benzoylcarbamimidoyl]benzamide | N-[benzamido(1,3-benzoxazol-2-ylimino)methyl]benzamide | SMR000147114 | cid_3846713 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H16N4O3 |
|---|
| Mol. Mass. | 384.3874 |
|---|
| SMILES | O=[#6](-[#7]\[#6](-[#7]-[#6](=O)-c1ccccc1)=[#7]/c1nc2ccccc2o1)-c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
