| Reaction Details |
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 | Report a problem with these data |
| Target | G-protein coupled receptor 84 |
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| Ligand | BDBM50239172 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1665432 (CHEMBL4015228) |
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| EC50 | 2680±n/a nM |
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| Citation |  Pillaiyar, T; Köse, M; Sylvester, K; Weighardt, H; Thimm, D; Borges, G; Förster, I; von Kügelgen, I; Müller, CE Diindolylmethane Derivatives: Potent Agonists of the Immunostimulatory Orphan G Protein-Coupled Receptor GPR84. J Med Chem60:3636-3655 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| G-protein coupled receptor 84 |
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| Name: | G-protein coupled receptor 84 |
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| Synonyms: | EX33 | G-protein coupled receptor 84 | GPR84 | GPR84_HUMAN | Inflammation-related G-protein coupled receptor EX33 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 43726.73 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_116040 |
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| Residue: | 396 |
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| Sequence: | MWNSSDANFSCYHESVLGYRYVAVSWGVVVAVTGTVGNVLTLLALAIQPKLRTRFNLLIA
NLTLADLLYCTLLQPFSVDTYLHLHWRTGATFCRVFGLLLFASNSVSILTLCLIALGRYL
LIAHPKLFPQVFSAKGIVLALVSTWVVGVASFAPLWPIYILVPVVCTCSFDRIRGRPYTT
ILMGIYFVLGLSSVGIFYCLIHRQVKRAAQALDQYKLRQASIHSNHVARTDEAMPGRFQE
LDSRLASGGPSEGISSEPVSAATTQTLEGDSSEVGDQINSKRAKQMAEKSPPEASAKAQP
IKGARRAPDSSSEFGKVTRMCFAVFLCFALSYIPFLLLNILDARVQAPRVVHMLAANLTW
LNGCINPVLYAAMNRQFRQAYGSILKRGPRSFHRLH
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| BDBM50239172 |
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| n/a |
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| Name | BDBM50239172 |
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| Synonyms: | CHEMBL4088884 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H10F4N2 |
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| Mol. Mass. | 318.2683 |
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| SMILES | Fc1cc(F)c2[nH]cc(Cc3c[nH]c4c(F)cc(F)cc34)c2c1 |
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| Structure | 
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