| Reaction Details |
|---|
 | Report a problem with these data |
| Target | D(2) dopamine receptor |
|---|
| Ligand | BDBM50001995 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_61411 |
|---|
| IC50 | 4.5±n/a nM |
|---|
| Citation |  Perregaard, J; Arnt, J; Bøgesø, KP; Hyttel, J; Sánchez, C Noncataleptogenic, centrally acting dopamine D-2 and serotonin 5-HT2 antagonists within a series of 3-substituted 1-(4-fluorophenyl)-1H-indoles. J Med Chem35:1092-101 (1992) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| D(2) dopamine receptor |
|---|
| Name: | D(2) dopamine receptor |
|---|
| Synonyms: | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2 |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 50931.60 |
|---|
| Organism: | Rattus norvegicus (rat) |
|---|
| Description: | P61169 |
|---|
| Residue: | 444 |
|---|
| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMS
RRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNS
AVNPIIYTTFNIEFRKAFMKILHC
|
|
|
|---|
| BDBM50001995 |
|---|
| n/a |
|---|
| Name | BDBM50001995 |
|---|
| Synonyms: | 2-{4-[5-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-yl]-piperidin-1-yl}-ethanol | CHEMBL430151 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H22ClFN2O |
|---|
| Mol. Mass. | 372.864 |
|---|
| SMILES | OCCN1CCC(CC1)c1cn(-c2ccc(F)cc2)c2ccc(Cl)cc12 |
|---|
| Structure | 
|
|---|
Search and Browse
