| Reaction Details |
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 | Report a problem with these data |
| Target | Galectin-3 |
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| Ligand | BDBM50247505 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1677821 (CHEMBL4027964) |
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| Kd | 22000±n/a nM |
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| Citation |  Peterson, K; Kumar, R; Stenström, O; Verma, P; Verma, PR; Håkansson, M; Kahl-Knutsson, B; Zetterberg, F; Leffler, H; Akke, M; Logan, DT; Nilsson, UJ Systematic Tuning of Fluoro-galectin-3 Interactions Provides Thiodigalactoside Derivatives with Single-Digit nM Affinity and High Selectivity. J Med Chem61:1164-1175 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Galectin-3 |
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| Name: | Galectin-3 |
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| Synonyms: | LEG3_HUMAN | LGALS3 | MAC2 |
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| Type: | Enzyme |
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| Mol. Mass.: | 26156.54 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P17931 |
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| Residue: | 250 |
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| Sequence: | MADNFSLHDALSGSGNPNPQGWPGAWGNQPAGAGGYPGASYPGAYPGQAPPGAYPGQAPP
GAYPGAPGAYPGAPAPGVYPGPPSGPGAYPSSGQPSATGAYPATGPYGAPAGPLIVPYNL
PLPGGVVPRMLITILGTVKPNANRIALDFQRGNDVAFHFNPRFNENNRRVIVCNTKLDNN
WGREERQSVFPFESGKPFKIQVLVEPDHFKVAVNDAHLLQYNHRVKKLNEISKLGISGDI
DLTSASYTMI
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| BDBM50247505 |
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| n/a |
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| Name | BDBM50247505 |
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| Synonyms: | CHEMBL4091660 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H22FN3O4S |
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| Mol. Mass. | 431.48 |
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| SMILES | Cc1ccc(S[C@@H]2O[C@H](CO)[C@H](O)[C@@H]([C@H]2O)n2cc(nn2)-c2cccc(F)c2)cc1 |r| |
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| Structure | 
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