Reaction Details |
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Target | Platelet-activating factor receptor |
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Ligand | BDBM50005227 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEBML_164926 |
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IC50 | 4.1±n/a nM |
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Citation | Carceller, E; Merlos, M; Giral, M; Bartrolí, J; García-Rafanell, J; Forn, J 4-substituted 2-alkoxytetrahydrofurans as potent and long-lasting PAF antagonists. J Med Chem35:676-83 (1992) [PubMed] |
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More Info.: | Get all data from this article, Assay Method |
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Platelet-activating factor receptor |
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Name: | Platelet-activating factor receptor |
Synonyms: | PAF-R | PTAFR | PTAFR_CAVPO | Platelet activating factor receptor | Platelet-activating factor receptor |
Type: | Protein |
Mol. Mass.: | 39005.63 |
Organism: | Cavia porcellus |
Description: | n/a |
Residue: | 342 |
Sequence: | MELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLT
VADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVK
YPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKG
SKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAV
FVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKF
RKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
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BDBM50005227 |
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n/a |
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Name | BDBM50005227 |
Synonyms: | 2-({Acetyl-[5-(6-decyloxy-hexyloxy)-tetrahydro-furan-3-ylmethoxycarbonyl]-amino}-methyl)-1-ethyl-pyridinium; iodide | CHEMBL421843 |
Type | Small organic molecule |
Emp. Form. | C32H55N2O6 |
Mol. Mass. | 563.7884 |
SMILES | CCCCCCCCCCOCCCCCCOC1CC(COC(=O)N(Cc2cccc[n+]2CC)C(C)=O)CO1 |
Structure |
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