| Reaction Details |
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 | Report a problem with these data |
| Target | Transmembrane domain-containing protein TMIGD3 |
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| Ligand | BDBM50259315 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1691289 (CHEMBL4041938) |
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| IC50 | 172±n/a nM |
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| Citation |  Poli, D; Falsini, M; Varano, F; Betti, M; Varani, K; Vincenzi, F; Pugliese, AM; Pedata, F; Dal Ben, D; Thomas, A; Palchetti, I; Bettazzi, F; Catarzi, D; Colotta, V Imidazo[1,2-a]pyrazin-8-amine core for the design of new adenosine receptor antagonists: Structural exploration to target the A Eur J Med Chem125:611-628 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Transmembrane domain-containing protein TMIGD3 |
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| Name: | Transmembrane domain-containing protein TMIGD3 |
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| Synonyms: | TMIG3_HUMAN | TMIGD3 | Transmembrane domain-containing protein TMIGD3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 30335.79 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_114868 |
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| Residue: | 266 |
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| Sequence: | MEGSPAGPIEQKEARWESSWEEQPDWTLGCLSPESQFRIPGLPGCILSFQLKVCFLPVMW
LFILLSLALISDAMVMDEKVKRSFVLDTASAICNYNAHYKNHPKYWCRGYFRDYCNIIAF
SPNSTNHVALRDTGNQLIVTMSCLTKEDTGWYWCGIQRDFARDDMDFTELIVTDDKGTLA
NDFWSGKDLSGNKTRSCKAPKVVRKADRSRTSILIICILITGLGIISVISHLTKRRRSQR
NRRVGNTLKPFSRVLTPKEMAPTEQM
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| BDBM50259315 |
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| n/a |
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| Name | BDBM50259315 |
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| Synonyms: | CHEMBL4069012 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H17N5O |
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| Mol. Mass. | 391.4247 |
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| SMILES | O=C(Nc1nc(cn2cc(nc12)-c1ccccc1)-c1ccccc1)c1cccnc1 |
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| Structure | 
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