| Reaction Details |
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 | Report a problem with these data |
| Target | Proteasome subunit beta type-1 |
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| Ligand | BDBM50259658 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_1691540 |
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| IC50 | 80±n/a nM |
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| Citation |  Han, LQ; Yuan, X; Wu, XY; Li, RD; Xu, B; Cheng, Q; Liu, ZM; Zhou, TY; An, HY; Wang, X; Cheng, TM; Ge, ZM; Cui, JR; Li, RT Urea-containing peptide boronic acids as potent proteasome inhibitors. Eur J Med Chem125:925-939 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Proteasome subunit beta type-1 |
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| Name: | Proteasome subunit beta type-1 |
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| Synonyms: | PSB1_HUMAN | PSC5 | PSMB1 | Proteasome component C5 | Proteasome subunit beta type-1/beta type-5 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 26493.62 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1366691 |
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| Residue: | 241 |
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| Sequence: | MLSSTAMYSAPGRDLGMEPHRAAGPLQLRFSPYVFNGGTILAIAGEDFAIVASDTRLSEG
FSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLTKIIEARLKMYKHSNNKAMTTGAIAAML
STILYSRRFFPYYVYNIIGGLDEEGKGAVYSFDPVGSYQRDSFKAGGSASAMLQPLLDNQ
VGFKNMQNVEHVPLSLDRAMRLVKDVFISAAERDVYTGDALRICIVTKEGIREETVSLRK
D
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| BDBM50259658 |
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| n/a |
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| Name | BDBM50259658 |
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| Synonyms: | CHEMBL4096371 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H28BN3O5 |
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| Mol. Mass. | 401.264 |
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| SMILES | CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)NCc1ccco1)B(O)O |r| |
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| Structure | 
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