| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Melatonin receptor type 1A |
|---|
| Ligand | BDBM50263699 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_1698238 |
|---|
| Ki | 62±n/a nM |
|---|
| Citation |  Rivara, S; Scalvini, L; Lodola, A; Mor, M; Caignard, DH; Delagrange, P; Collina, S; Lucini, V; Scaglione, F; Furiassi, L; Mari, M; Lucarini, S; Bedini, A; Spadoni, G Tetrahydroquinoline Ring as a Versatile Bioisostere of Tetralin for Melatonin Receptor Ligands. J Med Chem61:3726-3737 (2018) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Melatonin receptor type 1A |
|---|
| Name: | Melatonin receptor type 1A |
|---|
| Synonyms: | MTNR1A | MTNR1A protein | MTR1A_HUMAN | Mel-1A-R | Mel1a melatonin receptor | Melatonin 1A | Melatonin receptor | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin receptor type 1A |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 39392.94 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P48039 |
|---|
| Residue: | 350 |
|---|
| Sequence: | MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRN
AGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITG
IAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFA
QSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTM
FVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQ
NFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
|
|
|
|---|
| BDBM50263699 |
|---|
| n/a |
|---|
| Name | BDBM50263699 |
|---|
| Synonyms: | CHEMBL4061850 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H23NO |
|---|
| Mol. Mass. | 293.4027 |
|---|
| SMILES | CCC(=O)NC[C@@H]1CCc2ccccc2[C@H]1c1ccccc1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
