| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Glucose-dependent insulinotropic receptor |
|---|
| Ligand | BDBM50268608 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1705247 (CHEMBL4056480) |
|---|
| EC50 | >1000±n/a nM |
|---|
| Citation |  Koshizawa, T; Morimoto, T; Watanabe, G; Watanabe, T; Yamasaki, N; Sawada, Y; Fukuda, T; Okuda, A; Shibuya, K; Ohgiya, T Optimization of a novel series of potent and orally bioavailable GPR119 agonists. Bioorg Med Chem Lett27:3249-3253 (2017) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Glucose-dependent insulinotropic receptor |
|---|
| Name: | Glucose-dependent insulinotropic receptor |
|---|
| Synonyms: | G-protein coupled receptor 119 (GPR119) | GP119_HUMAN | GPR119 | Glucose-dependent insulinotropic receptor |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 36901.49 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q8TDV5 |
|---|
| Residue: | 335 |
|---|
| Sequence: | MESSFSFGVILAVLASLIIATNTLVAVAVLLLIHKNDGVSLCFTLNLAVADTLIGVAISG
LLTDQLSSPSRPTQKTLCSLRMAFVTSSAAASVLTVMLITFDRYLAIKQPFRYLKIMSGF
VAGACIAGLWLVSYLIGFLPLGIPMFQQTAYKGQCSFFAVFHPHFVLTLSCVGFFPAMLL
FVFFYCDMLKIASMHSQQIRKMEHAGAMAGGYRSPRTPSDFKALRTVSVLIGSFALSWTP
FLITGIVQVACQECHLYLVLERYLWLLGVGNSLLNPLIYAYWQKEVRLQLYHMALGVKKV
LTSFLLFLSARNCGPERPRESSCHIVTISSSEFDG
|
|
|
|---|
| BDBM50268608 |
|---|
| n/a |
|---|
| Name | BDBM50268608 |
|---|
| Synonyms: | CHEMBL4072360 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C24H29FN4O5S |
|---|
| Mol. Mass. | 504.574 |
|---|
| SMILES | CN(c1ccc(cc1F)S(C)(=O)=O)c1ncnc2c(coc12)C1CCN(CC1)C(=O)OC(C)(C)C |
|---|
| Structure | 
|
|---|
Search and Browse
