| Reaction Details |
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 | Report a problem with these data |
| Target | Glucose-dependent insulinotropic receptor |
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| Ligand | BDBM50268639 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1705245 (CHEMBL4056478) |
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| EC50 | 19±n/a nM |
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| Citation |  Koshizawa, T; Morimoto, T; Watanabe, G; Watanabe, T; Yamasaki, N; Sawada, Y; Fukuda, T; Okuda, A; Shibuya, K; Ohgiya, T Optimization of a novel series of potent and orally bioavailable GPR119 agonists. Bioorg Med Chem Lett27:3249-3253 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Glucose-dependent insulinotropic receptor |
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| Name: | Glucose-dependent insulinotropic receptor |
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| Synonyms: | G-protein coupled receptor 119 (GPR119) | GP119_HUMAN | GPR119 | Glucose-dependent insulinotropic receptor |
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| Type: | Protein |
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| Mol. Mass.: | 36901.49 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q8TDV5 |
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| Residue: | 335 |
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| Sequence: | MESSFSFGVILAVLASLIIATNTLVAVAVLLLIHKNDGVSLCFTLNLAVADTLIGVAISG
LLTDQLSSPSRPTQKTLCSLRMAFVTSSAAASVLTVMLITFDRYLAIKQPFRYLKIMSGF
VAGACIAGLWLVSYLIGFLPLGIPMFQQTAYKGQCSFFAVFHPHFVLTLSCVGFFPAMLL
FVFFYCDMLKIASMHSQQIRKMEHAGAMAGGYRSPRTPSDFKALRTVSVLIGSFALSWTP
FLITGIVQVACQECHLYLVLERYLWLLGVGNSLLNPLIYAYWQKEVRLQLYHMALGVKKV
LTSFLLFLSARNCGPERPRESSCHIVTISSSEFDG
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| BDBM50268639 |
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| n/a |
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| Name | BDBM50268639 |
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| Synonyms: | CHEMBL4099566 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H26FN7O4S |
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| Mol. Mass. | 491.539 |
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| SMILES | CC(C)(C)OC(=O)N1CCC(CC1)n1nnc2c(Nc3ccc(cc3F)S(C)(=O)=O)ncnc12 |
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| Structure | 
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