| Reaction Details |
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 | Report a problem with these data |
| Target | Cholecystokinin receptor type A |
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| Ligand | BDBM50013195 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_50034 |
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| IC50 | 4800±n/a nM |
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| Citation |  Bock, MG; DiPardo, RM; Evans, BE; Rittle, KE; Whitter, WL; Veber, DF; Freidinger, RM; Chang, RS; Chen, TB; Lotti, VJ Cholecystokinin-A receptor ligands based on the kappa-opioid agonist tifluadom. J Med Chem33:450-5 (1990) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Cholecystokinin receptor type A |
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| Name: | Cholecystokinin receptor type A |
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| Synonyms: | CCKAR_RAT | Cckar | Cholecystokinin peripheral | Cholecystokinin receptor | Cholecystokinin receptor type A |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 49676.37 |
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| Organism: | RAT |
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| Description: | Cholecystokinin central 0 RAT::P30551 |
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| Residue: | 444 |
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| Sequence: | MSHSPARQHLVESSRMDVVDSLLMNGSNITPPCELGLENETLFCLDQPQPSKEWQSALQI
LLYSIIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLK
DFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICRPLQSRVWQTKSHALKVIAAT
WCLSFTIMTPYPIYSNLVPFTKNNNQTANMCRFLLPSDAMQQSWQTFLLLILFLLPGIVM
VVAYGLISLELYQGIKFDASQKKSAKEKKPSTGSSTRYEDSDGCYLQKSRPPRKLELQQL
SSGSGGSRLNRIRSSSSAANLIAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTVSAE
KHLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGPPGVRGEVGEEE
DGRTIRALLSRYSYSHMSTSAPPP
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| BDBM50013195 |
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| n/a |
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| Name | BDBM50013195 |
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| Synonyms: | CHEMBL140749 | Thiophene-3-carboxylic acid [5-(2-fluoro-phenyl)-1-methyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-2-ylmethyl]-amide |
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| Type | Small organic molecule |
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| Emp. Form. | C22H22FN3OS |
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| Mol. Mass. | 395.493 |
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| SMILES | CN1C(CNC(=O)c2ccsc2)CNC(c2ccccc2F)c2ccccc12 |
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| Structure | 
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