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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Bifunctional epoxide hydrolase 2 | ||
| Ligand | BDBM50274167 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1713980 (CHEMBL4124029) | ||
| IC50 | 356±n/a nM | ||
| Citation |  Burmistrov, V; Morisseau, C; Pitushkin, D; Karlov, D; Fayzullin, RR; Butov, GM; Hammock, BD Adamantyl thioureas as soluble epoxide hydrolase inhibitors. Bioorg Med Chem Lett28:2302-2313 (2018) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Bifunctional epoxide hydrolase 2 | |||
| Name: | Bifunctional epoxide hydrolase 2 | ||
| Synonyms: | Ephx2 | Epoxide hydrolase 2 | HYES_RAT | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 62337.15 | ||
| Organism: | Rattus norvegicus | ||
| Description: | ChEMBL_1465995 | ||
| Residue: | 554 | ||
| Sequence: |
| ||
| BDBM50274167 | |||
| n/a | |||
| Name | BDBM50274167 | ||
| Synonyms: | CHEMBL4127661 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C17H22N2S | ||
| Mol. Mass. | 286.435 | ||
| SMILES | S=C(NC1C2CC3CC(C2)CC1C3)Nc1ccccc1 |TLB:9:8:12:5.4.3,9:4:7.8.10:12,THB:3:4:7:10.11.12,3:11:7:5.9.4,2:3:7.8.10:12,(59.84,-37.47,;59.82,-35.93,;58.48,-35.17,;57.15,-35.96,;57.13,-37.49,;55.73,-37.84,;54.4,-37.35,;53.2,-38.63,;54.7,-38.21,;56.13,-38.78,;54.7,-36.62,;55.74,-35.38,;54.39,-35.86,;61.15,-35.14,;62.49,-35.9,;62.5,-37.44,;63.84,-38.19,;65.17,-37.41,;65.15,-35.86,;63.8,-35.11,)| | ||
| Structure | 
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