| Reaction Details |
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 | Report a problem with these data |
| Target | Alpha-1A adrenergic receptor |
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| Ligand | BDBM50274054 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1713733 (CHEMBL4123782) |
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| Ki | 0.501187±n/a nM |
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| Citation |  Sagratini, G; Buccioni, M; Marucci, G; Poggesi, E; Skorski, M; Costanzi, S; Giardinà, D Chiral analogues of (+)-cyclazosin as potent? Bioorg Med Chem26:3502-3513 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Alpha-1A adrenergic receptor |
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| Name: | Alpha-1A adrenergic receptor |
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| Synonyms: | ADA1A_HUMAN | ADRA1A | ADRA1C | Adrenergic alpha1A | Alpha 1A-adrenoceptor | Alpha 1A-adrenoreceptor | Alpha adrenergic receptor 1a | Alpha-1C adrenergic receptor | Alpha-adrenergic receptor 1c | Cerebral cortex alpha adrenergic receptor | adrenergic Alpha1 | adrenergic Alpha1C |
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| Type: | Cell-surface receptors |
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| Mol. Mass.: | 51511.67 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P35348 |
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| Residue: | 466 |
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| Sequence: | MVFLSGNASDSSNCTQPPAPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSV
THYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCII
SIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQPAPEDETICQINE
EPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKN
APAGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPD
FKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLCRKQSSKHALGYTL
HPPSQAVEGQHKDMVRIPVGSRETFYRISKTDGVCEWKFFSSMPRGSARITVSKDQSSCT
TARVRSKSFLQVCCCVGPSTPSLDKNHQVPTIKVHTISLSENGEEV
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| BDBM50274054 |
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| n/a |
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| Name | BDBM50274054 |
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| Synonyms: | CHEMBL4128084 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H31N5O4 |
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| Mol. Mass. | 477.5554 |
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| SMILES | [H][C@@]12CCCC[C@]1([H])N(CCN2C(=O)OCc1ccccc1)c1nc(N)c2cc(OC)c(OC)cc2n1 |r| |
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| Structure | 
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