| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2a |
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| Ligand | BDBM50275599 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1714794 (CHEMBL4124843) |
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| IC50 | 7.6±n/a nM |
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| Citation |  Varano, F; Catarzi, D; Falsini, M; Vincenzi, F; Pasquini, S; Varani, K; Colotta, V Identification of novel thiazolo[5,4-d]pyrimidine derivatives as human A Bioorg Med Chem26:3688-3695 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2a |
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| Name: | Adenosine receptor A2a |
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| Synonyms: | A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 44716.46 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P29274 |
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| Residue: | 412 |
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| Sequence: | MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAI
PFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTR
AKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYF
NFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVG
LFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFR
KIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNG
YALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
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| BDBM50275599 |
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| n/a |
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| Name | BDBM50275599 |
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| Synonyms: | CHEMBL4127213 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H17N5OS |
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| Mol. Mass. | 363.436 |
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| SMILES | COc1ccccc1CNc1nc(N)c2nc(sc2n1)-c1ccccc1 |
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| Structure | 
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