| Reaction Details |
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 | Report a problem with these data |
| Target | NAD-dependent protein deacylase sirtuin-6 |
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| Ligand | BDBM50276140 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1715366 (CHEMBL4125415) |
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| IC50 | >200000±n/a nM |
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| Citation |  Wang, C; Wang, F; Chen, X; Zou, Y; Zhu, H; Zhao, Q; Shen, J; Li, Y; Li, Y; He, B The mimics of N Bioorg Med Chem Lett28:2375-2378 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| NAD-dependent protein deacylase sirtuin-6 |
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| Name: | NAD-dependent protein deacylase sirtuin-6 |
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| Synonyms: | NAD-dependent protein deacetylase sirtuin-6 | NAD-dependent protein deacetylase sirtuin-6 (SIRT6) | Regulatory protein SIR2 homolog 6 | SIR2-like protein 6 | SIR2L6 | SIR6_HUMAN | SIRT6 | Sirtuin-6 (SIRT6) |
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| Type: | Protein |
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| Mol. Mass.: | 39133.03 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q8N6T7 |
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| Residue: | 355 |
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| Sequence: | MSVNYAAGLSPYADKGKCGLPEIFDPPEELERKVWELARLVWQSSSVVFHTGAGISTASG
IPDFRGPHGVWTMEERGLAPKFDTTFESARPTQTHMALVQLERVGLLRFLVSQNVDGLHV
RSGFPRDKLAELHGNMFVEECAKCKTQYVRDTVVGTMGLKATGRLCTVAKARGLRACRGE
LRDTILDWEDSLPDRDLALADEASRNADLSITLGTSLQIRPSGNLPLATKRRGGRLVIVN
LQPTKHDRHADLRIHGYVDEVMTRLMKHLGLEIPAWDGPRVLERALPPLPRPPTPKLEPK
EESPTRINGSIPAGPKQEPCAQHNGSEPASPKRERPTSPAPHRPPKRVKAKAVPS
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| BDBM50276140 |
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| n/a |
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| Name | BDBM50276140 |
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| Synonyms: | CHEMBL4129995 |
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| Type | Small organic molecule |
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| Emp. Form. | C34H51N3O3S |
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| Mol. Mass. | 581.852 |
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| SMILES | CCCCCCCCCCCCCC(=S)NCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1ccccc1 |r| |
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| Structure | 
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