| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma intracellular receptor 2 |
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| Ligand | BDBM321279 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1716892 (CHEMBL4131892) |
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| Ki | >1200±n/a nM |
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| Citation |  Donnier-Maréchal, M; Carato, P; Larchanché, PE; Ravez, S; Boulahjar, R; Barczyk, A; Oxombre, B; Vermersch, P; Melnyk, P Synthesis and pharmacological evaluation of benzamide derivatives as potent and selective sigma-1 protein ligands. Eur J Med Chem138:964-978 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma intracellular receptor 2 |
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| Name: | Sigma intracellular receptor 2 |
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| Synonyms: | MAC30 | Meningioma-associated protein 30 | S2R | SGMR2_HUMAN | Sigma-2 receptor | Sigma2 receptor | TMEM97 | Transmembrane protein 97 |
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| Type: | Protein |
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| Mol. Mass.: | 20857.20 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q5BJF2 |
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| Residue: | 176 |
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| Sequence: | MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQ
EPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLF
EDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK
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| BDBM321279 |
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| n/a |
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| Name | BDBM321279 |
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| Synonyms: | N-[3-(benzylmethylamino)propyl]-3-methoxybenzamide | US10179761, Compound 3.1.28 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H24N2O2 |
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| Mol. Mass. | 312.4061 |
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| SMILES | COc1cccc(c1)C(=O)NCCCN(C)Cc1ccccc1 |
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| Structure | 
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