| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Squalene monooxygenase |
|---|
| Ligand | BDBM50015504 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_201924 |
|---|
| IC50 | >400000±n/a nM |
|---|
| Citation |  Sen, SE; Wawrzenczyk, C; Prestwich, GD Inhibition of vertebrate squalene epoxidase by extended and truncated analogues of trisnorsqualene alcohol. J Med Chem33:1698-701 (1990) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Squalene monooxygenase |
|---|
| Name: | Squalene monooxygenase |
|---|
| Synonyms: | ERG1 | ERG1_HUMAN | SE | SQLE | Squalene epoxidase |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 63936.94 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_201924 |
|---|
| Residue: | 574 |
|---|
| Sequence: | MWTFLGIATFTYFYKKFGDFITLANREVLLCVLVFLSLGLVLSYRCRHRNGGLLGRQQSG
SQFALFSDILSGLPFIGFFWAKSPPESENKEQLEARRRRKGTNISETSLIGTAACTSTSS
QNDPEVIIVGAGVLGSALAAVLSRDGRKVTVIERDLKEPDRIVGEFLQPGGYHVLKDLGL
GDTVEGLDAQVVNGYMIHDQESKSEVQIPYPLSENNQVQSGRAFHHGRFIMSLRKAAMAE
PNAKFIEGVVLQLLEEDDVVMGVQYKDKETGDIKELHAPLTVVADGLFSKFRKSLVSNKV
SVSSHFVGFLMKNAPQFKANHAELILANPSPVLIYQISSSETRVLVDIRGEMPRNLREYM
VEKIYPQIPDHLKEPFLEATDNSHLRSMPASFLPPSSVKKRGVLLLGDAYNMRHPLTGGG
MTVAFKDIKLWRKLLKGIPDLYDDAAIFEAKKSFYWARKTSHSFVVNILAQALYELFSAT
DDSLHQLRKACFLYFKLGGECVAGPVGLLSVLSPNPLVLIGHFFAVAIYAVYFCFKSEPW
ITKPRALLSSGAVLYKACSVIFPLIYSEMKYMVH
|
|
|
|---|
| BDBM50015504 |
|---|
| n/a |
|---|
| Name | BDBM50015504 |
|---|
| Synonyms: | 5,9,13-Trimethyl-tetradeca-4,8,12-trien-1-ol | CHEMBL48139 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H30O |
|---|
| Mol. Mass. | 250.4195 |
|---|
| SMILES | [#6]\[#6](-[#6])=[#6]/[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#6]-[#8] |
|---|
| Structure | 
|
|---|
Search and Browse
