| Reaction Details |
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 | Report a problem with these data |
| Target | Histone acetyltransferase KAT2B |
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| Ligand | BDBM43307 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1724426 (CHEMBL4139704) |
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| IC50 | 12000±n/a nM |
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| Citation |  Wapenaar, H; van den Bosch, T; Leus, NGJ; van der Wouden, PE; Eleftheriadis, N; Hermans, J; Hailu, GS; Rotili, D; Mai, A; Dömling, A; Bischoff, R; Haisma, HJ; Dekker, FJ The relevance of K Eur J Med Chem136:480-486 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Histone acetyltransferase KAT2B |
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| Name: | Histone acetyltransferase KAT2B |
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| Synonyms: | Histone acetyltransferase KAT2A/KAT2B | Histone acetyltransferase PCAF | KAT2B | KAT2B_HUMAN | PCAF |
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| Type: | PROTEIN |
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| Mol. Mass.: | 93045.76 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1502838 |
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| Residue: | 832 |
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| Sequence: | MSEAGGAGPGGCGAGAGAGAGPGALPPQPAALPPAPPQGSPCAAAAGGSGACGPATAVAA
AGTAEGPGGGGSARIAVKKAQLRSAPRAKKLEKLGVYSACKAEESCKCNGWKNPNPSPTP
PRADLQQIIVSLTESCRSCSHALAAHVSHLENVSEEEMNRLLGIVLDVEYLFTCVHKEED
ADTKQVYFYLFKLLRKSILQRGKPVVEGSLEKKPPFEKPSIEQGVNNFVQYKFSHLPAKE
RQTIVELAKMFLNRINYWHLEAPSQRRLRSPNDDISGYKENYTRWLCYCNVPQFCDSLPR
YETTQVFGRTLLRSVFTVMRRQLLEQARQEKDKLPLEKRTLILTHFPKFLSMLEEEVYSQ
NSPIWDQDFLSASSRTSQLGIQTVINPPPVAGTISYNSTSSSLEQPNAGSSSPACKASSG
LEANPGEKRKMTDSHVLEEAKKPRVMGDIPMELINEVMSTITDPAAMLGPETNFLSAHSA
RDEAARLEERRGVIEFHVVGNSLNQKPNKKILMWLVGLQNVFSHQLPRMPKEYITRLVFD
PKHKTLALIKDGRVIGGICFRMFPSQGFTEIVFCAVTSNEQVKGYGTHLMNHLKEYHIKH
DILNFLTYADEYAIGYFKKQGFSKEIKIPKTKYVGYIKDYEGATLMGCELNPRIPYTEFS
VIIKKQKEIIKKLIERKQAQIRKVYPGLSCFKDGVRQIPIESIPGIRETGWKPSGKEKSK
EPRDPDQLYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNR
YYVSKKLFMADLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIKEAGLIDK
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| BDBM43307 |
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| n/a |
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| Name | BDBM43307 |
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| Synonyms: | 4-methyl-N-(4-oxidanylnaphthalen-1-yl)benzenesulfonamide | N-(4-hydroxy-1-naphthalenyl)-4-methylbenzenesulfonamide | N-(4-hydroxy-1-naphthyl)-4-methyl-benzenesulfonamide | N-(4-hydroxynaphthalen-1-yl)-4-methylbenzenesulfonamide | PC-0599222 | PCMD-CC-MCM-218 | cid_832572 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H15NO3S |
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| Mol. Mass. | 313.371 |
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| SMILES | Cc1ccc(cc1)S(=O)(=O)Nc1ccc(O)c2ccccc12 |
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| Structure | 
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