| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Prolyl hydroxylase EGLN2 |
|---|
| Ligand | BDBM118339 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_1733860 |
|---|
| IC50 | 480±n/a nM |
|---|
| Citation |  Joharapurkar, AA; Pandya, VB; Patel, VJ; Desai, RC; Jain, MR Prolyl Hydroxylase Inhibitors: A Breakthrough in the Therapy of Anemia Associated with Chronic Diseases. J Med Chem61:6964-6982 (2018) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Prolyl hydroxylase EGLN2 |
|---|
| Name: | Prolyl hydroxylase EGLN2 |
|---|
| Synonyms: | EGLN2 | EGLN2_HUMAN | EIT6 | Egl nine homolog 2 | Estrogen-induced tag 6 | HIF prolyl hydroxylase | HIF-PH1 | HIF-prolyl hydroxylase 1 | HPH-3 | Hypoxia-inducible factor prolyl hydroxylase | PHD1 | Prolyl hydroxylase domain-containing protein 1 | Prolyl hydroxylase domain-containing protein 1 (PHD1) |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 43657.01 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q96KS0 |
|---|
| Residue: | 407 |
|---|
| Sequence: | MDSPCQPQPLSQALPQLPGSSSEPLEPEPGRARMGVESYLPCPLLPSYHCPGVPSEASAG
SGTPRATATSTTASPLRDGFGGQDGGELRPLQSEGAAALVTKGCQRLAAQGARPEAPKRK
WAEDGGDAPSPSKRPWARQENQEAEREGGMSCSCSSGSGEASAGLMEEALPSAPERLALD
YIVPCMRYYGICVKDSFLGAALGGRVLAEVEALKRGGRLRDGQLVSQRAIPPRSIRGDQI
AWVEGHEPGCRSIGALMAHVDAVIRHCAGRLGSYVINGRTKAMVACYPGNGLGYVRHVDN
PHGDGRCITCIYYLNQNWDVKVHGGLLQIFPEGRPVVANIEPLFDRLLIFWSDRRNPHEV
KPAYATRYAITVWYFDAKERAAAKDKYQLASGQKGVQVPVSQPPTPT
|
|
|
|---|
| BDBM118339 |
|---|
| n/a |
|---|
| Name | BDBM118339 |
|---|
| Synonyms: | US8653111, 72 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C13H14N8O2 |
|---|
| Mol. Mass. | 314.3027 |
|---|
| SMILES | O=c1c(c[nH]n1-c1cc(ncn1)N1CCOCC1)-n1ccnn1 |
|---|
| Structure | 
|
|---|
Search and Browse
