| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Prolyl hydroxylase EGLN3 |
|---|
| Ligand | BDBM118339 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_1733869 |
|---|
| IC50 | 450±n/a nM |
|---|
| Citation |  Joharapurkar, AA; Pandya, VB; Patel, VJ; Desai, RC; Jain, MR Prolyl Hydroxylase Inhibitors: A Breakthrough in the Therapy of Anemia Associated with Chronic Diseases. J Med Chem61:6964-6982 (2018) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Prolyl hydroxylase EGLN3 |
|---|
| Name: | Prolyl hydroxylase EGLN3 |
|---|
| Synonyms: | EGLN3 | EGLN3_HUMAN | Egl nine homolog 3 (EGLIN3) | Egl nine homolog 3 (EGLN3) |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 27265.54 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q9H6Z9 |
|---|
| Residue: | 239 |
|---|
| Sequence: | MPLGHIMRLDLEKIALEYIVPCLHEVGFCYLDNFLGEVVGDCVLERVKQLHCTGALRDGQ
LAGPRAGVSKRHLRGDQITWIGGNEEGCEAISFLLSLIDRLVLYCGSRLGKYYVKERSKA
MVACYPGNGTGYVRHVDNPNGDGRCITCIYYLNKNWDAKLHGGILRIFPEGKSFIADVEP
IFDRLLFFWSDRRNPHEVQPSYATRYAMTVWYFDAEERAEAKKKFRNLTRKTESALTED
|
|
|
|---|
| BDBM118339 |
|---|
| n/a |
|---|
| Name | BDBM118339 |
|---|
| Synonyms: | US8653111, 72 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C13H14N8O2 |
|---|
| Mol. Mass. | 314.3027 |
|---|
| SMILES | O=c1c(c[nH]n1-c1cc(ncn1)N1CCOCC1)-n1ccnn1 |
|---|
| Structure | 
|
|---|
Search and Browse
