| Reaction Details |
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 | Report a problem with these data |
| Target | Solute carrier family 15 member 1 |
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| Ligand | BDBM50449807 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1740626 (CHEMBL4156376) |
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| Ki | 210000±n/a nM |
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| Citation |  Foley, DW; Pathak, RB; Phillips, TR; Wilson, GL; Bailey, PD; Pieri, M; Senan, A; Meredith, D Thiodipeptides targeting the intestinal oligopeptide transporter as a general approach to improving oral drug delivery. Eur J Med Chem156:180-189 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Solute carrier family 15 member 1 |
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| Name: | Solute carrier family 15 member 1 |
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| Synonyms: | Intestinal H(+)/peptide cotransporter | Oligopeptide transporter, small intestine isoform | PEPT1 | Peptide transporter 1 | S15A1_RABIT | SLC15A1 | Solute carrier family 15 member 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 78931.16 |
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| Organism: | Oryctolagus cuniculus |
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| Description: | ChEMBL_109684 |
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| Residue: | 707 |
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| Sequence: | MGMSKSLSCFGYPLSIFFIVVNEFCERFSYYGMRALLILYFRNFIGWDDNLSTVIYHTFV
ALCYLTPILGALIADAWLGKFKTIVWLSIVYTIGQAVTSLSSVNELTDNNHDGTPDSLPV
HVAVCMIGLLLIALGTGGIKPCVSAFGGDQFEEGQEKQRNRFFSIFYLAINAGSLLSTII
TPMVRVQQCGIHVKQACYPLAFGIPAILMAVSLIVFIIGSGMYKKFKPQGNILSKVVKCI
CFAIKNRFRHRSKQFPKRAHWLDWAKEKYDERLIAQIKMVTRVLFLYIPLPMFWALFDQQ
GSRWTLQATTMSGRIGILEIQPDQMQTVNTILIIILVPIMDAVVYPLIAKCGLNFTSLKK
MTIGMFLASMAFVAAAILQVEIDKTLPVFPKANEVQIKVLNVGSENMIISLPGQTVTLNQ
MSQTNEFMTFNEDTLTSINITSGSQVTMITPSLEAGQRHTLLVWAPNNYRVVNDGLTQKS
DKGENGIRFVNTYSQPINVTMSGKVYEHIASYNASEYQFFTSGVKGFTVSSAGISEQCRR
DFESPYLEFGSAYTYLITSQATGCPQVTEFEDIPPNTMNMAWQIPQYFLITSGEVVFSIT
GLEFSYSQAPSNMKSVLQAGWLLTVAVGNIIVLIVAGAGQINKQWAEYILFAALLLVVCV
IFAIMARFYTYVNPAEIEAQFEEDEKKKNPEKNDLYPSLAPVSQTQM
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| BDBM50449807 |
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| n/a |
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| Name | BDBM50449807 |
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| Synonyms: | CHEMBL4168781 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H30N2O8S |
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| Mol. Mass. | 494.558 |
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| SMILES | COc1c(C)c2COC(=O)c2c(O)c1C\C=C(/C)CCC(=O)OC[C@H](NC(=S)[C@H](C)N)C(O)=O |r| |
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| Structure | 
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