| Reaction Details |
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 | Report a problem with these data |
| Target | Probable L-lysine-epsilon aminotransferase |
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| Ligand | BDBM50450930 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1744139 (CHEMBL4178649) |
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| IC50 | 1150±n/a nM |
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| Citation |  Reshma, RS; Jeankumar, VU; Kapoor, N; Saxena, S; Bobesh, KA; Vachaspathy, AR; Kolattukudy, PE; Sriram, D Mycobacterium tuberculosis lysine-?-aminotransferase a potential target in dormancy: Benzothiazole based inhibitors. Bioorg Med Chem25:2761-2771 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Probable L-lysine-epsilon aminotransferase |
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| Name: | Probable L-lysine-epsilon aminotransferase |
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| Synonyms: | 2.6.1.36 | L-lysine aminotransferase | LAT_MYCTU | Lysine 6-aminotransferase | Probable L-lysine-epsilon aminotransferase | lat |
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| Type: | PROTEIN |
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| Mol. Mass.: | 49007.52 |
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| Organism: | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) |
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| Description: | ChEMBL_105536 |
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| Residue: | 449 |
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| Sequence: | MAAVVKSVALAGRPTTPDRVHEVLGRSMLVDGLDIVLDLTRSGGSYLVDAITGRRYLDMF
TFVASSALGMNPPALVDDREFHAELMQAALNKPSNSDVYSVAMARFVETFARVLGDPALP
HLFFVEGGALAVENALKAAFDWKSRHNQAHGIDPALGTQVLHLRGAFHGRSGYTLSLTNT
KPTITARFPKFDWPRIDAPYMRPGLDEPAMAALEAEALRQARAAFETRPHDIACFVAEPI
QGEGGDRHFRPEFFAAMRELCDEFDALLIFDEVQTGCGLTGTAWAYQQLDVAPDIVAFGK
KTQVCGVMAGRRVDEVADNVFAVPSRLNSTWGGNLTDMVRARRILEVIEAEGLFERAVQH
GKYLRARLDELAADFPAVVLDPRGRGLMCAFSLPTTADRDELIRQLWQRAVIVLPAGADT
VRFRPPLTVSTAEIDAAIAAVRSALPVVT
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| BDBM50450930 |
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| n/a |
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| Name | BDBM50450930 |
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| Synonyms: | CHEMBL4210409 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H12N2O5S |
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| Mol. Mass. | 416.406 |
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| SMILES | OC(=O)c1cc(cc(c1)-c1ccc(\C=C(/C#N)c2nc3ccccc3s2)o1)C(O)=O |
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| Structure | 
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