| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine deaminase |
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| Ligand | BDBM50451177 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1744716 (CHEMBL4179226) |
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| Ki | 1.1±n/a nM |
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| Citation |  Kandalkar, SR; Ramaiah, PA; Joshi, M; Wavhal, A; Waman, Y; Raje, AA; Tambe, A; Ansari, S; De, S; Palle, VP; Mookhtiar, KA; Deshpande, AM; Barawkar, DA Modifications of flexible nonyl chain and nucleobase head group of (+)-erythro-9-(2's-hydroxy-3's-nonyl)adenine [(+)-EHNA] as adenosine deaminase inhibitors. Bioorg Med Chem25:5799-5819 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine deaminase |
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| Name: | Adenosine deaminase |
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| Synonyms: | ADA | ADA_BOVIN | Adenosine aminohydrolase |
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| Type: | Enzyme |
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| Mol. Mass.: | 40910.44 |
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| Organism: | Bos taurus (bovine) |
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| Description: | n/a |
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| Residue: | 363 |
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| Sequence: | MAQTPAFNKPKVELHVHLDGAIKPETILYYGRKRGIALPADTPEELQNIIGMDKPLSLPE
FLAKFDYYMPAIAGCREAVKRIAYEFVEMKAKDGVVYVEVRYSPHLLANSKVEPIPWNQA
EGDLTPDEVVSLVNQGLQEGERDFGVKVRSILCCMRHQPSWSSEVVELCKKYREQTVVAI
DLAGDETIEGSSLFPGHVKAYAEAVKSGVHRTVHAGEVGSANVVKEAVDTLKTERLGHGY
HTLEDATLYNRLRQENMHFEVCPWSSYLTGAWKPDTEHPVVRFKNDQVNYSLNTDDPLIF
KSTLDTDYQMTKNEMGFTEEEFKRLNINAAKSSFLPEDEKKELLDLLYKAYGMPSPASAE
QCL
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| BDBM50451177 |
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| n/a |
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| Name | BDBM50451177 |
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| Synonyms: | CHEMBL4210264 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H18F3N5O |
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| Mol. Mass. | 365.3529 |
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| SMILES | C[C@H](O)[C@@H](CCc1cccc(c1)C(F)(F)F)n1cnc2c(N)ncnc12 |r| |
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| Structure | 
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